Results 81 to 90 of about 2,229 (260)

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source

Reduction of sawtooth amplitude by resonant magnetic perturbation [PDF]

Nuclear Fusion, 2020
Jianchao Li, Yonghua Ding, Qingquan Yu, Nengchao Wang, Da Li, Xiaoqing Zhang, Dongliang Han, Zhipeng Chen, Zhoujun Yang, Song Zhou, Wei Yan, Yunfeng Liang, Xiaolong Zhang, Xiaodong Lin, Huibin Sun, Xiang Gao, Jiangang Li   +16 more
openaire   +2 more sources

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Small resonant magnetic perturbations result in three-dimensional material transport in the fusion plasma edge

Nuclear Fusion
Erosion patterns in a 3D magnetic topology are significantly altered when compared to an axisymmetric scenario due to differences in the impurity transport in a plasma environment.
Marcos Navarro, Juri Romazanov, Andreas Kirschner, Jonathan Van Blarcum, Edward Hinson, Tyler Abrams, Oliver Schmitz   +6 more
doaj   +1 more source

Nanoplatforms for Sentinel and Tumor‐Draining Lymph Node Mapping: From Visualization to Pathway‐Informed Staging

Advanced Healthcare Materials, EarlyView.
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen, Nina Li, Meiyan Zou, Zihao Zhou, Rongwei Xu, Weiyao Feng, Xinyuan Zhao, Li Cui   +7 more
wiley   +1 more source

First observation of edge impurity behavior with n = 1 RMP application in EAST L-mode plasma

Nuclear Fusion
High-Z impurity accumulation suppression and mitigation in core plasma is frequently observed in EAST edge localized mode mitigation experiments by using resonant magnetic perturbations (RMP) coils.
Wenmin Zhang, Ling Zhang, Yunxin Cheng, Shigeru Morita, Hui Sheng, Darío Mitnik, Youwen Sun, Zhengxiong Wang, Yuqi Chu, Ailan Hu, Yinxian Jie, Haiqing Liu   +11 more
doaj   +1 more source

Influence of kinetic effects on plasma response to resonant magnetic perturbations in HL-2A tokamak

He jishu
BackgroundThe control of edge localized modes (ELMs) is a key issue for the safety operation of ITER and future magnetic confinement fusion reactors.
LIU Yihuizi, ZHANG Neng, LIU Yueqiang, GONG Xueyu, WANG Shuo, LI Chunyu, WANG Lian, HAO Guangzhou   +7 more
doaj   +1 more source

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

Advanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco, Roberto Baretta, Andrea Di Fonzo, Andrea Armirotti, Stefano Cinti, Mara Mirasoli, Marco Frasconi, Claudia Corbo   +7 more
wiley   +1 more source

Response of a magnetically diverted tokamak plasma to a resonant magnetic perturbation

Nuclear Fusion
Abstract The safety-factor profile of a magnetically diverted tokamak plasma diverges logarithmically as the magnetic separatrix (a.k.a. the last closed magnetic flux-surface) is approached. At first sight, this suggests that, when determining the response of such a plasma to a static, externally generated ...
openaire   +2 more sources

A Lightweight, 3D‐Printable, Low‐Cost, “One‐Click” Dorsal Skin Window for High‐Quality Long‐Term Multimodal Subcutaneous Tumor Imaging

Advanced Healthcare Materials, EarlyView.
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez, Xabier Morales Urteaga, Maider Esparza, Lucía Grande, Ainhoa Urbiola, Cristina Ederra, Tomas Muñoz Santoro, Beatrice Pinci, Alvaro Teijeira, Carlos Ortiz de Solórzano   +9 more
wiley   +1 more source