Results 101 to 110 of about 181,834 (300)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Improved qubit bifurcation readout in the straddling regime of circuit QED

open access: yes, 2012
We study bifurcation measurement of a multi-level superconducting qubit using a nonlinear resonator biased in the straddling regime, where the resonator frequency sits between two qubit transition frequencies.
A. Blais   +6 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Study and analysis of an electric Z-shaped meta-atom

open access: yesAdvanced Electromagnetics, 2012
A printed Z-shaped electric meta-atom is presented as an alternative design to the conventional electric-LC (ELC) resonator. We propose to redesign the ELC resonator pattern to get a compact and a low cost electric resonator exhibiting a strong electric ...
A. Dhouibi   +3 more
doaj   +1 more source

Superconducting Qubits Coupled to Torsional Resonators

open access: yes, 2010
We propose a scheme of strong and tunable coupling between a superconducting phase qubit and nanomechanical torsional resonator. In our scheme the torsional resonator directly modulates the largest energy scale (the Josephson coupling energy) of the ...
Choi, Jae-Hyuk   +2 more
core   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

The Bright Side of Coulomb Blockade

open access: yes, 2011
We explore the photonic (bright) side of dynamical Coulomb blockade (DCB) by measuring the radiation emitted by a dc voltage-biased Josephson junction embedded in a microwave resonator.
D. Esteve   +8 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim   +3 more
wiley   +1 more source

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