Results 11 to 20 of about 2,239 (183)

Fenchone Derivatives as a Novel Class of CB2 Selective Ligands: Design, Synthesis, X-ray Structure and Therapeutic Potential

Molecules, 2022
A series of novel cannabinoid-type derivatives were synthesized by the coupling of (1S,4R)-(+) and (1R,4S)-(−)-fenchones with various resorcinols/phenols.
Reem Smoum, Christeene Haj, Shira Hirsch, Alina Nemirovski, Zhannah Yekhtin, Benny Bogoslavsky, Gaganjyot Kaur Bakshi, Mukesh Chourasia, Ruth Gallily, Joseph Tam, Raphael Mechoulam   +10 more
doaj   +1 more source

Contact Allergy Induced by Mango (Mangifera indica): A Relevant Topic?

Medicina, 2021
Introduction: The most common clinical manifestation of mango allergy is contact dermatitis, which can be localized or systemic. The sensitising substances that have long been suspected are alk(en)yl catechols and/or alk(en)yl resorcinols.
Elena Camelia Berghea, Mihai Craiu, Selda Ali, Sabina Loredana Corcea, Roxana Silvia Bumbacea   +4 more
doaj   +1 more source

Co-crystalization and in vitro biological characterization of 5-Aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole Hsp90 inhibitors [PDF]

, 2012
A potential therapeutic strategy for targeting cancer that has gained much interest is the inhibition of the ATP binding and ATPase activity of the molecular chaperone Hsp90.
Chrisostomos Prodromou, Daumantas Matulis, Egidijus Kazlauskas, Inga Čikotienė, Paul Workman, S. Mark Roe, Swee Y. Sharp, Wenqing Xu   +7 more
core   +7 more sources

The Azotobacter vinelandii AlgU regulon during vegetative growth and encysting conditions: A proteomic approach.

PLoS ONE, 2023
In the Pseduomonadacea family, the extracytoplasmic function sigma factor AlgU is crucial to withstand adverse conditions. Azotobacter vinelandii, a closed relative of Pseudomonas aeruginosa, has been a model for cellular differentiation in Gram-negative
Sangita Chowdhury-Paul, Iliana C Martínez-Ortíz, Victoria Pando-Robles, Soledad Moreno, Guadalupe Espín, Enrique Merino, Cinthia Núñez   +6 more
doaj   +1 more source

Alkyl resorcinols in grains from plants from the family Gramineae

Acta Societatis Botanicorum Poloniae, 2014
5-n-alkylresorcinols were found in 22 of the 27 studied species of grasses. In Agropyron caninum and Bromus macrostachys only the content of alkyl resorcinols was determined, in Agropyron repens, Bromus mollis and Elymus arenarius the composition of ...
Grzegorz Kubus, Franciszek Tłuścik
doaj   +1 more source

New Alkylpyridinium Anthraquinone, Isocoumarin, C-Glucosyl Resorcinol Derivative and Prenylated Pyranoxanthones from the Culture of a Marine Sponge-Associated Fungus, Aspergillus stellatus KUFA 2017

Marine Drugs, 2022
An unreported isocoumarin, (3S,4R)-4-hydroxy-6-methoxymellein (2), an undescribed propylpyridinium anthraquinone (4), and an unreported C-glucosyl resorcinol derivative, acetyl carnemycin E (5c), were isolated, together with eight previously reported ...
Fátima P. Machado, Inês C. Rodrigues, Luís Gales, José A. Pereira, Paulo M. Costa, Tida Dethoup, Sharad Mistry, Artur M. S. Silva, Vitor Vasconcelos, Anake Kijjoa   +9 more
doaj   +1 more source

Palaeoenvironmental reconstruction of Northern Spain during the last 8000 cal yr BP based on the biomarker content of the Roñanzas peat bog (Asturias) [PDF]

, 2010
We determined the lipid distributions (n-alkanes, n-methyl ketones, n-alkanoic acids, 5-n-alkyl resorcinols and sterols) and total organic carbon (TOC) content in a 2.0 m deep Sp/wgmim-dominated ombrotrophic peat bog in Northern Spain.
Torres Pérez-Hidalgo, Trinidad José
core   +2 more sources

Antidermatophytic Action of Resorcinol Derivatives: Ultrastructural Evidence of the Activity of Phenylethyl Resorcinol against Microsporum gypseum

Molecules, 2016
In this work, we evaluated the antidermatophytic activities of three resorcinol derivatives that have a history of use in dermo-cosmetic applications to discover molecules with multiple dermatological activities (i.e., multi-target drugs), thereby ...
Carlo Romagnoli, Anna Baldisserotto, Chiara B. Vicentini, Donatella Mares, Elisa Andreotti, Silvia Vertuani, Stefano Manfredini   +6 more
doaj   +1 more source

Identification and Characterization of a New Type III Polyketide Synthase from a Marine Yeast, Naganishia uzbekistanensis

Marine Drugs, 2020
A putative Type III Polyketide synthase (PKSIII) encoding gene was identified from a marine yeast, Naganishia uzbekistanensis strain Mo29 (UBOCC-A-208024) (formerly named as Cryptococcus sp.) isolated from deep-sea hydrothermal vents.
Laure Martinelli, Vanessa Redou, Bastien Cochereau, Ludovic Delage, Nolwenn Hymery, Elisabeth Poirier, Christophe Le Meur, Gaetan Le Foch, Lionel Cladiere, Mohamed Mehiri, Nathalie Demont-Caulet, Laurence Meslet-Cladiere   +11 more
doaj   +1 more source

Chemical Composition and Biological Activity of Argentinian Propolis of Four Species of Stingless Bees

Molecules, 2022
The chemical composition of propolis of four species of stingless bees (SLBs) from Argentina was determined, and its antibacterial and anticancer activity was evaluated on selected types of microbes and cancer cell lines.
Valery A. Isidorov, Jolanta Maslowiecka, Lukasz Szoka, Naldo Pellizzer, Dora Miranda, Ewa Olchowik-Grabarek, Monika Zambrzycka, Izabela Swiecicka   +7 more
doaj   +1 more source