Results 41 to 50 of about 318,669 (306)
Local and generalized bone loss in rheumatoid arthritis
Современная ревматология, 2021 The article presents a review of cross-sectional studies and long-term prospective observations dedicated to changes in bone mineral density (BMD) in patients with rheumatoid arthritis (RA) and factors influencing it.
P. S. Kovalenko +4 more
doaj +1 more source
Morphology of resorption of apical cement in destructive forms of periodontitis in the acute stage
Эндодонтия Today, 2022 Aim. To study morphology of external resorption of apical root area of teeth with destructive forms of apical periodontitis in the acute stage.Materials and methods.
V. V. Glinkin +7 more
doaj +1 more source
Transient Local Bone Remodeling Effects of rhBMP-2 in an Ovine Interbody Spine Fusion Model [PDF]
, 2016 Background: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is a powerful osteoinductive morphogen capable of stimulating the migration of mesenchymal stem cells (MSCs) to the site of implantation and inducing the proliferation and ...
Badura, Jeffrey +7 more
core +1 more source
Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption [PDF]
, 2019 Vav1 is a Rho/Rac guanine nucleotide exchange factor primarily expressed in hematopoietic cells. In this study, we investigated the potential role of Vav1 in osteoclast (OC) differentiation by comparing the ability of bone marrow mononuclear cells (BMMCs)
Cha, Young-Nam +6 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates [PDF]
, 2017 The design of synthetic bone grafts to foster bone formation is a challenge in regenerative medicine. Understanding the interaction of bone substitutes with osteoclasts is essential, since osteoclasts not only drive a timely resorption of the biomaterial,
Avnet, Sofia +7 more
core +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Fe-doped tricalcium phosphates: crystal structure and degradation behavior
Materials Research Express, 2020 β -tricalcium phosphate ( β -TCP, Ca3(PO4)2) is biodegradable ceramics with chemical and mineral compositions similar to those of bone. It is a potential candidate for bone repair surgery, and substituting the Fe ions can improve its biological behavior.
Kyung-Hyeon Yoo +4 more
doaj +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Microflora and periodontal disease
Dental Research Journal, 2012 Background: Periodontitis is a disease that affects and destroys the tissues that support teeth. Tissue damage results from a prolonged inflammatory response to an ecological shift in the composition of subgingival biofilms.
Luca Scapoli +7 more
doaj +1 more source