Results 161 to 170 of about 40,368,284 (333)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

A Resource-Based Analysis of IT Oursourcing [PDF]

This paper studies the relationships between the choice of a sourcing mode for information systems, the value of the resources used in systems development activities and the presence of those resources at sufficient level within the firm.
Benoit A. Aubert, Vital Roy
core  

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Superior performance, managerial comprehension and resource-based strategies [PDF]

The cross-sectional study looks at how firms develop superior performance using their internal resources. It is a study based on the resource-based view of the firm. The study looks at firms in the Motor Vehicle Manufacturing Industry in UK.
Zvobgo, Gilbert
core  

ESTRATÉGIAS COMPETITIVAS EM INSTITUIÇÕES DE ENSINO SUPERIOR: UM ESTUDO DE CASO À LUZ DA VISÃO BASEADA EM RECURSOS

Revista Gestão Universitária na América Latina, 2017
This study sought to highlight the resources used by an institution of higher education in the pursuit of competitive advantage, based on the precepts of the resource - based view.
David Rodrigo Petry, Darlan José Roman, Citania Aparecida Pilatti, Carolini Danieli Martins Scheffer Demeterko, Ieda Margarete Oro   +4 more
doaj  

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Community-based natural resource management (CBNRM) in Africa - A review

, 2001
Metadata only recordThe purpose of this work was to characterize the nature of CBNRM experiences, their evolution over time, and to develop analytical tools on determinants of success, uptake, and expansion.
Josserand, H. P.
core  

Examining the impact of green marketing practices on business performance: A synergistic application of resource-based view and triple bottom line theory. [PDF]

PLoS One
Babu MA, Rouf MA, Islam MR, Islam M.
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source