Results 61 to 70 of about 4,229,632 (303)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Lightweight and Resource-Constrained Learning Network for Face Recognition with Performance Optimization

Sensors, 2020
Despite considerable progress in face recognition technology in recent years, deep learning (DL) and convolutional neural networks (CNN) have revealed commendable recognition effects with the advent of artificial intelligence and big data.
Hsiao-Chi Li, Zong-Yue Deng, Hsin-Han Chiang   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

AIDS Resource Center commercial with Lauren Hutton

, 1989
Video footage from the Resource Center LGBT Collection. The video is an AIDS Resource Center commercial with Lauren Hutton.
AIDS Resource Center
core   +1 more source

Soft-labelling for budget-constrained semantic segmentation: Bringing coherence to label down-sampling

Computational Visual Media
In semantic segmentation, training data down-sampling is commonly performed due to resource limitations, the need to adapt image size to the model input, or to improve data augmentation.
Roberto Alcover-Couso, Marcos Escudero-Viñolo, Juan C. SanMiguel, José M. Martinez   +3 more
doaj   +1 more source

Resource News issue: spring 1999 [PDF]

, 1999
The spring 1999 issue of Resource News, which was a community newsletter from the Child Care Resource and Referral office of Washington County ...
Washington County Child Care Resource and Referral (Or.)
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Heterogeneous impacts and transmission mechanisms of perceived development barriers on cooperative management performance: micro evidence from Shaanxi, China

Frontiers in Sustainable Food Systems
IntroductionFarmer cooperatives are key to linking smallholders with modern agriculture, yet how different development barriers affect their management performance remains unclear, as prior studies focus mainly on classifying barriers.MethodsUsing survey
Shihan Chen, Sihan Jiang, Haiyan Wang, Jikun Ma   +3 more
doaj   +1 more source

Scheduling Under Labour Resource Constraints

, 2015
In this paper we introduce an optimization problem extracted from an industrial application: the scheduling problem under labour constraints. After giving a short summary of the origins of this problem and its mathematical formulation, the different ...
De Souza C.C., Cavalcante C.C.B., Colombani Y., Heipcke S.   +3 more
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