Results 41 to 50 of about 31,882 (224)

LEADERSHIP, GOOD GOVERNANCE AND DEVELOPMENT IN NIGERIA

open access: yesInternational Studies Journal, 2023
The success or failure of governance in any regime in power is basically determined by the quality of leadership of such administration. The study of the connection between leadership and good governance for national development has become essential ...
ADENIYI ADEKUNLE
doaj  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Structure, Physicochemical, and Functional Properties of Dietary Fiber Extracts Obtained from Agriophyllum squarrosum Seed and Quinoa

open access: yesShipin gongye ke-ji
It was of great significance to explore new dietary fiber resources with excellent functional activity from available materials in nature for improving human diet level based on quinoa dietary fiber, the structure, by Fourier transform infrared ...
Siwen NIU   +6 more
doaj   +1 more source

Identifying and Prioritizing Behavioral Factors Affecting the Selection of Investment Portfolios of Holding Companies [PDF]

open access: yesپژوهش‌های روانشناختی در مدیریت
Purpose: In the realm of investment management, selecting an appropriate investment portfolio for holding companies constitutes one of the most critical decisions.
Mohammad Ebrahim Raei Ezabadi   +1 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Why are healthcare top managers cynical? The effects of feeling powerless, role overload, and resilience

open access: yesActa Psychologica
Background: Sense of power is a vital leadership resource for managing job demands and sustaining organisational effectiveness in healthcare. However, Top Management Healthcare Professionals (TMHPs) may perceive a lack of power despite holding positional
Adedeji David Lawal   +5 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Aggression and dominance in cichlids in resident-intruder tests: the role of environmental enrichment

open access: yesNeotropical Ichthyology, 2011
When establishing dominance residents have a greater likelihood to dominate intruders than vice versa, partially because the resident has more to loose that the intruder has to win. This is known as the prior residency effect.
Vincent Nijman, Boudewijn A. Heuts
doaj  

Effects of Different Extraction Methods on Physicochemical, Functional Properties, and Structure of Dietary Fiber from Dragon Fruit Peel

open access: yesShipin gongye ke-ji
To reduce resource waste and enhance the utilization of dragon fruit peel, the study employed acid hydrolysis (A-SDF), enzymatic hydrolysis (E-SDF), and ultrasound-assisted extraction (U-SDF) to isolate soluble dietary fiber (SDF) from red-fleshed dragon
Jiaqi GU   +7 more
doaj   +1 more source

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