Results 61 to 70 of about 5,395,077 (299)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Procedures and Resources Plan

, 2009
The D4Science-II project aims to build a Knowledge Ecosystem by promoting, defining, and implementing interoperability between the D4Science e-Infrastructure and other data e-Infrastructures. This Ecosystem will therefore be composed by multiple resources of different nature, provided by geographically distributed organizations. In order to create such
Andrade P., Manzi A., Pagano P.
openaire   +2 more sources

Corporate minerals and community development dilemma in the Surat Resource Region, Australia: Implications for resource development planning

, 2017
While the idea that agricultural farmlands and natural resources exploration can co-exist is rhetorically sound, emerged and rising realities question this claim.
Michael Odei Erdiaw-Kwasie, Khorshed Alam, Erdiaw-Kwasie, Michael, Alam, Khorshed   +3 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Evaluation of tree stump measurement methods for estimating diameter at breast height and tree height

International Journal of Applied Earth Observations and Geoinformation
The estimation of diameter at breast height (DBH) and tree height from stump dimensions plays a crucial role in assessing the economic and environmental impacts resulting from illegal logging or natural disasters.
Milan Koreň, Ľubomír Scheer, Róbert Sedmák, Marek Fabrika   +3 more
doaj   +1 more source

Resource Planning For Rescue Operations

CoRR, 2016
After an earthquake, disaster sites pose a multitude of health and safety concerns. A rescue operation of people trapped in the ruins after an earthquake disaster requires a series of intelligent behavior, including planning. For a successful rescue operation, given a limited number of available actions and regulations, the role of planning in rescue ...
Mona Khaffaf, Arshia Khaffaf
openaire   +3 more sources

Advanced resource planning as decision support module to ERP. [PDF]

In this paper, we show that the planning and decision-support capabilities of the MPC (Manufacturing Planning and Control) system, which forms the core of any ERP (Enterprise Resource Planning) package, may be substantively enhanced by including a ...
Lambrecht, Marc, Van Nieuwenhuyse, Inneke, De Boeck, Liesje, Vandaele, Nico   +3 more
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source