Results 81 to 90 of about 47,876 (303)

Multi‐Dimensional Synergistic Engineering for Boosting Nanozyme Catalysis

open access: yesAdvanced Science, EarlyView.
This review systematically analyzes cutting‐edge strategies for boosting nanozyme catalysis through multi‐dimensional synergistic engineering, containing morphology, electronic structure modulation, external stimulation, and machine learning‐aided design.
Yuechun Li   +6 more
wiley   +1 more source

Analyses of GWAS and Sub‐Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk

open access: yesAdvanced Science, EarlyView.
A cost‐effective strategy is developed analyzing sub‐threshold GWAS loci (5 × 10−8 < P ≤ 10−6), identifying 180 risk loci and 304 high‐confidence genes through combined GWAS/subGWAS analysis. This approach reveals dendrite development and morphogenesis (DDM) as a novel SCZ pathway.
Rui Chen   +15 more
wiley   +1 more source

GRIDCC: Real-time workflow system [PDF]

open access: yes, 2007
The Grid is a concept which allows the sharing of resources between distributed communities, allowing each to progress towards potentially different goals.
Akram, A   +7 more
core  

Stage‐Resolved Phosphoproteomic Landscape of Mouse Spermiogenesis Reveals Key Kinase Signaling in Sperm Morphogenesis

open access: yesAdvanced Science, EarlyView.
The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu   +25 more
wiley   +1 more source

Deficiency of Leucine‐Rich Repeat Containing G Protein‐Coupled Receptor 4 in Pancreas Reduces β Cell Mass

open access: yesAdvanced Science, EarlyView.
In islet β cells, LGR4 binds with Rspondin to activate the Wnt‐β‐catenin‐Ccnd1 axis, leading to a subsequent increase in cell proliferation. On the other hand, LGR4 also binds with RANKL, thus suppressing the phosphorylation of p44/p42 MAPK and p65 NF‐κB and subsequent cell apoptosis.
Chao Luo   +8 more
wiley   +1 more source

Fundamentals and Perspectives on Materials for Bifunctional Electrocatalysis

open access: yesAdvanced Science, EarlyView.
This review presents a comparative evaluation of key catalyst families for HER and OER, including MOFs, metal oxides, hydroxides/hydrides, carbon‐based materials, phosphides, and chalcogenides. Their electrochemical activity, stability, and commercialization potential are critically analyzed, with design strategies for hybrid catalysts also discussed ...
Iqra Fareed   +8 more
wiley   +1 more source

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