Results 61 to 70 of about 3,945,792 (293)
Economic evidence for the prevention and treatment of atopic eczema: a protocol for a systematic review [PDF]
, 2016 Background: Eczema, synonymous with atopic eczema or atopic dermatitis, is a chronic skin disease that has a similar impact on health-related quality of life as other chronic diseases.
AS Paller +18 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Scale Purification and Validation: A Methodological Approach to Sustainable Online Retailing
Vikalpa, 2022 Sustainability in the e-commerce business has created an overwhelming interest among practitioners and researchers. The different business models adopted by the e-retailers in India lack sustainable aspects, hindering them from generating sustainable ...
Suhail Ahmad Bhat +2 more
doaj +1 more source
The Temporal Logic of the Tower Chief System [PDF]
, 1990 The purpose is to describe the logic used in the reasoning scheme employed in the Tower Chief system, a runway configuration management system. First, a review of classical logic is given.
Hazelton, Lyman R., Jr.
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Estimating the burden of rheumatoid arthritis in Africa:A systematic analysis [PDF]
, 2012 Rheumatoid arthritis (RA) has an estimated worldwide prevalence of 1%. It is one of the leading causes of chronic morbidity in the developed world, but little is known about the disease burden in Africa. RA is often seen as a minor health problem and has
Abdel-Nasser +32 more
core +3 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source