Results 41 to 50 of about 5,531,290 (284)

Classification-based resource selection [PDF]

open access: yesProceedings of the 18th ACM conference on Information and knowledge management, 2009
In some retrieval situations, a system must search across multiple collections. This task, referred to as federated search, occurs for example when searching a distributed index or aggregating content for web search. Resource selection refers to the subtask of deciding, given a query, which collections to search.
Jaime Arguello   +2 more
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Seasonal patterns of habitat use by a mesopredator in boreal forest landscapes fragmented by fire

open access: yesEcosphere
Wildfire is the most impactful disturbance regime in the North American boreal region, driving the structure and composition of forests across the region.
Derek A. Arnold   +6 more
doaj   +1 more source

Bootstrap estimation of resource selection probability functions [PDF]

open access: yes, 2013
Resource selection functions (RSFs) are used for quantify how animals are selective in the use of the habitat period or food. A Resource Selection Probability Function (RSPF) can be estimated if N, the total number of units in the population, and n1 the ...
Sandra V. Cardozo   +2 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Den‐site characteristics and selection by brown bears (Ursus arctos) in the central Brooks Range of Alaska

open access: yesEcosphere, 2019
Selection and use of dens is a critical behavioral adaption of bears (Ursus spp.) to survive extended periods of resource limitation. We analyzed selection of den sites by brown bears (Ursus arctos) in an arctic montane environment from 2014 to 2017.
Mathew S. Sorum   +5 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Home Range and Habitat Selection of Feral Horses (Equus ferus f. caballus) in a Mountainous Environment: A Case Study from Northern Greece

open access: yesLand
The spatial ecology of feral horses (Equus ferus f. caballus) in Greece has never been studied before, including home range size and habitat selection. We tracked two mares fitted with global positioning system collars between September 2020 and August ...
Dimitrios E. Bakaloudis   +6 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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