Results 81 to 90 of about 5,638,188 (290)

Partial Niche Partitioning in Three Sympatric Gull Species Through Foraging Areas and Habitat Selection

Ecology and Evolution
Anthropogenic habitat change is having a detrimental impact on biodiversity worldwide, altering the foraging behaviour and population dynamics of many species.
Nina J. O'Hanlon, Gary D. Clewley, Daniel T. Johnston, Chris B. Thaxter, Samuel Langlois Lopez, Lucy R. Quinn, Philipp H. Boersch‐Supan, Elizabeth A. Masden, Francis Daunt, Jared Wilson, Niall H. K. Burton, Elizabeth M. Humphreys   +11 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Comparation of logistic regression methods and discrete choice model in the selection of habitats Comparação dos métodos regressão logística e modelo de escolha discreta na seleção de habitats

Scientia Agricola, 2010
Based on a review of most recent data analyses on resource selection by animals as well as on recent suggestions that indicate the lack of an unified statistical theory that shows how resource selection can be detected and measured, the authors suggest ...
Sandra Vergara Cardozo, Bryan Frederick John Manly, Carlos Tadeu dos Santos Dias   +2 more
doaj   +1 more source

AIDS Resource Center commercial with Randy Moore

, 1989
Video footage from the Resource Center LGBT Collection. The video is an AIDS Resource Center commercial with Randy Moore and his family.
AIDS Resource Center
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Resource News issue: summer 1999 [PDF]

, 1999
The summer 1999 issue of Resource News, which was a community newsletter from the Child Care Resource and Referral office of Washington County ...
Washington County Child Care Resource and Referral (Or.)
core   +1 more source

Influence of visual perception on movement decisions by an ungulate prey species

Biology Open, 2023
Blaise A. Newman, Jordan R. Dyal, Karl V. Miller, Michael J. Cherry, Gino J. D'Angelo   +4 more
doaj   +1 more source

AIDS Resource Center commercial with Jan Miller

, 1989
Video footage from the Resource Center LGBT Collection. The video is an AIDS Resource Center commercial with literary agent Jan Miller.
AIDS Resource Center
core