Results 91 to 100 of about 1,780,875 (305)

Productive Efficiency in Water Usage: An Analysis of Differences among Farm Types and Sizes in Georgia [PDF]

In Georgia, the price of irrigation water is equal to the cost of extraction, including pumping and diversion, storage, treatment, and delivery costs. These water-pricing conditions are repeated in locales around the world.
Moore, Rebecca, Price, Joseph
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

IS EQUITY A CONSTRAINT? APPLICATIONS TO BLOCK RATE AND OTHER PRICING SCHEMES WITH HETEROGENEOUS USERS [PDF]

In this paper, we model the trade-off between equity and efficiency in a market for a resource when users of that resource are heterogeneous. We develop the analytical model, and show that under certain circumstances efficiency can be achieved in a ...
Schoengold, Karina, Zilberman, David
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Economic profitability and efficiency of honey production from the Asian honeybee (Apis cerana) in the mid-hills of Nepal

Journal of Agriculture and Food Research
Beekeeping is a prominent industry in the Myagdi district of Nepal, with significant potential for commercial expansion through modern practices. Access to regional productivity and profitability information is pivotal for adopting new technologies and ...
Anup Paudel, Narayan Prasad Tiwari, Suryamani Dhungana, Logan L. Britton   +3 more
doaj   +1 more source

Efficiency and sustainability of land-resource use on a small island

Environmental Research Letters, 2019
Land resources are essential for humans to survive, and different methods of land- resource use depend largely on the local natural context and society.
Keigo Noda, Akiko Iida, Satoshi Watanabe, Kazutoshi Osawa   +3 more
doaj   +1 more source

The Dematerialization Potential of the Australian Economy [PDF]

In this paper we test the long term dematerialization potential for Australia in terms of materials, energy, and water use as well as CO2 emissions, by introducing concrete targets for major sectors.
Graham M Turner, Heinz Schandl
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Use Efficiency of Primary Energy Resources in Turkey

Energy Exploration & Exploitation, 2013
The demand for electrical energy in Turkey, which is increasing due to population growth and industrialization like in the rest of the world, can only be met by either increasing the amount of energy produced with existing resources or by reducing energy consumption, on the basis of energy efficiency at every stage of production to consumption in ...
Kasap, Yaşar, Duman, Fehmi
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source