Results 51 to 60 of about 339,280 (262)

Reduction of Natural Resource Use by Improving Resource Efficiency [PDF]

Universal Journal of Materials Science, 2016
In 2011, the German Association of Engineers (VDI) started working on a set of guidelines dealing with the improvement of resource efficiency. These guidelines represent a framework that defines resource efficiency and outlines proposals for the producing industry. A special guideline for small and medium-sized enterprises (SMEs) is included as well as
Franz-Georg Simon, Olaf Holm
openaire   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Influence of varying nitrogen levels on crop productivity, profitability and resource-use efficiency in Bt-cotton (Gossypium hirsutum) in semi-arid region of Afghanistan

The Indian Journal of Agricultural Sciences, 2019
Cotton (Gossypium hirsutum L.) is one of the most important commercial crops of Afghanistan mainly grown for fiber production; however, its seeds are used as source of edible oil while cotton cake is used as animal feed.
GHULAM HABIB NOORI, ANIL K CHOUDHARY, ANCHAL DASS   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Efficiency Evaluation of Using Resources by Hospital Units

EUROPEAN RESEARCH STUDIES JOURNAL, 2020
Purpose: The aim of this article is to present an efficient evaluation methodology for the hospital resources used in a study on units of healthcare system and their analysis in the organizational and legal forms. Design/Methodology/Approach: A research group constituted 48 health care units has been used.
Cwiakala-Malys, Anna, Lagowski, Pawel, Durbajlo-Mrowiec, Malgorzata, Kuzminski, Lukasz, Rolczynski, Tomasz   +4 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Increased plant density and reduced N rate lead to more grain yield and higher resource utilization in summer maize

Journal of Integrative Agriculture, 2016
Planting at an optimum density and supplying adequate nitrogen (N) to achieve higher yields is a common practice in crop production, especially for maize (Zea mays L.); however, excessive N fertilizer supply in maize production results in reduced N use ...
De-yang SHI, Yan-hong LI, Ji-wang ZHANG, Peng LIU, Bin ZHAO, Shu-ting DONG   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Effect of foliar application of nutrients on wheat (Triticum aestivum) crop performance, economics, resource use efficiency and soil properties under rainfed conditions

The Indian Journal of Agricultural Sciences, 2020
Field studies were conducted during rabi season of 2015–16 to 2017–18 at research farm of Advanced Centre for Rainfed Agriculture, SKUAST-Jammu to study the effect of foliar application of nutrients on crop performance, economics, resource use ...
VIKAS ABROL, A P SINGH, ANIL KUMAR, RAVINDER CHARY, CH SRINIVASARAO, PEEYUSH SHARMA, BRINDER SINGH, SANJEEV SALGOTRA, JAI KAPOOR, HEMANT DADHICH   +9 more
doaj   +1 more source