Results 91 to 100 of about 26,473 (309)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evaluating the fit and performance of flat-fold, cup, and three-panel respirators among Thai healthcare personnel

Frontiers in Public Health
IntroductionHealthcare personnel (HCP) face high risks of airborne infections, including coronavirus disease 2019 (COVID-19), tuberculosis, and measles.
Kampanat Wangsan, Kampanat Wangsan, Ratana Sapbamrer, Ratana Sapbamrer, Wachiranun Sirikul, Wachiranun Sirikul, Wuttipat Kiratipaisarl, Krongporn Ongprasert, Pheerasak Assavanopakun, Pheerasak Assavanopakun, Vithawat Surawattanasakul, Vithawat Surawattanasakul, Amornphat Kitro, Amornphat Kitro, Jinjuta Panumasvivat, Jinjuta Panumasvivat, Amnart Wongcharoen   +16 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

From Comfort to Protection: Quantitative Comparison of Fit and Air Permeability in Textile Masks and Respirators

Textiles
The present study examines the influence of material and structural parameters on the fit and air permeability of textile face masks, surgical masks, and certified respirators.
Maria Ivanova, Radostina A. Angelova
doaj   +1 more source

N95 Respirator

, 2023
3M disposable particulate respirator with an exhalation valve. It has an N95 rating.

core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

PAUSES IN RESPIRATION. [PDF]

The Lancet, 1880
n ...
openaire   +2 more sources

P95 Respirator

, 2023
3M disposable particulate respirator with an exhalation valve. It has an P95 rating.

core  

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source