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Respiratory Acidosis

2015
: Most causes of respiratory acidosis are due to hypoventilation, not increased CO2 production. Respiratory insufficiency causes hypoxemia, which can lead to a secondary metabolic acidosis. The early phase of respiratory acidosis is associated with severe acidemia in acute respiratory failure.
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Acetazolamide teratogenesis: Interation of maternal metabolic and respiratory acidosis in the induction of ectrodactyly in C57BL/6J mice

, 1984
Exposure of C57BL/6J mice to 20% CO2 for 8 hours on day 10 of gestation has been shown to produce right-sided postaxial forelimb ectrodactyly in 23% of the offspring. Carbon dioxide exposure produces a dramatic increase in maternal plasma CO2 accompanied
T. Weaver, W. Scott
semanticscholar   +1 more source

Dual contribution theory of regulation of CSF HCO3 in respiratory acidosis.

Journal of applied physiology, 1976
Regulation of CSF HCO3-in respiratory acidosis was studied in light of the "dual contribution theory," which proposed that there were two sources for the CSF HCO3-increase: 1) HCO3-by diffusion from plasma and 2) HCO3-generated in the CNS and catalyzed ...
F. Hasan, H. Kazemi
semanticscholar   +1 more source

EFFECTS OF ACIDOSIS ON RESPIRATORY FUNCTION*

Annals of the New York Academy of Sciences, 1965
Summary and ConclusionsThe net effect of acidosis on the respiratory apparatus is an elevation of ventilation‐perfusion ratios. Alveolar ventilation is augmented; perfusion of the well‐ventilated portion of the lung is enhanced, while perfusion of the poorly ventilated space is diminished.
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The mechanics of breathing in respiratory acidosis

Experientia, 1973
Nachweis, dass Inhalation von Luftgemisch mit 10% CO2 bei wachen Kaninchen eine bronchiale Konstriktion verursacht, wenn die Lungendehnung selbst von niedrigem Blut pH begleitet ist. Erhohung von CO2 allein erschlafft die Bronchien und unterdruckt teilweise die Bronchienkontraktion, was mit dem niedrigen Blut pH zusammenhangt.
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Glutamine transport in basolateral vesicles from dogs with acute respiratory acidosis.

American Journal of Physiology, 1984
It has been shown that acute respiratory acidosis in dogs results in enhanced renal extraction of L-glutamine from plasma and increased ammonia excretion per nephron.
D. Windus, S. Klahr, M. Hammerman
semanticscholar   +1 more source

Effects of metabolic and respiratory acidosis on bone

Current Opinion in Nephrology and Hypertension, 1993
Acidosis had long been thought to influence the bone mineral; however, there was little direct evidence to support this impression. When neonatal mouse calvariae are cultured for 3 hours in medium with a reduced bicarbonate concentration, a model of acute metabolic acidosis, there is net calcium efflux from bone in addition to a net influx of protons ...
David A. Bushinsky, Yaacov Ori
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The Effects of Respiratory Acidosis in the Chick Embryo

Journal of Experimental Biology, 1971
ABSTRACT Embryos of the domestic fowl have been incubated in normal conditions and in an atmosphere of 9 % carbon dioxide from day 9 onwards. There is a rapid increase in blood bicarbonate and base excess when the embryos are exposed to carbon dioxide.
C. M. Dawes, K. Simkiss
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Net calcium efflux from live bone during chronic metabolic, but not respiratory, acidosis.

American Journal of Physiology, 1989
In vivo chronic metabolic acidosis induces bone mineral dissolution. Whether the dissolution is due to alterations in physicochemical factors alone, as in acute metabolic acidosis, or requires participation of bone cells is not clear.
D. A. Bushinsky
semanticscholar   +1 more source

Metabolic, but not respiratory, acidosis increases bone PGE(2) levels and calcium release.

AJP - Renal Physiology, 2001
A decrease in blood pH may be due to either a reduction in bicarbonate concentration ([HCO(3)(-)]; metabolic acidosis) or to an increase in PCO(2) (respiratory acidosis).
D. Bushinsky   +3 more
semanticscholar   +1 more source

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