Results 121 to 130 of about 12,340,249 (385)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Airway Organoid Models as Pivotal Tools for Unraveling Molecular Mechanisms and Therapeutic Targets in Respiratory Diseases: A Literature Review

open access: yesTherapeutics and Clinical Risk Management
Shu-Ping Jiang,1,* Bing-Qi Lin,1,* Xing-Qiang Zhou,2,* Min-Hua Li,1,* Zhen-Cheng Feng,1 Yue-Ying Qin,1 Shi-Qi Lin,1 Zi-Qing Zhou,1 Yang Peng,1 Lian Li1 1State Key Laboratory of Respiratory Disease, National Clinical ...
Jiang SP   +9 more
doaj  

Respiratory diseases [PDF]

open access: yesPostgraduate Medical Journal, 1990
D G, James, O M, Sharma
openaire   +2 more sources

Understanding the Twentieth Century Decline in Chronic Conditions Among Older Men [PDF]

open access: yes
I use a sample of Union Army veterans to trace the impact of a high infant mortality rate in area of enlistment, such infectious disease as acute respiratory infections, measles, typhoid fever, tuberculosis, rheumatic fever, diarrhea, and malaria while ...
Dora L. Costa
core  

Rearing calves outdoors with and without calf jackets compared with indoor housing on calf health and live-weight performance [PDF]

open access: yes, 2004
peer-reviewedThe objective of this study was to compare the effects of rearing calves outdoors, with and without all-weather calf jackets, with calves reared indoors on calf immunity and animal performance. In February 1999, male Holstein calves (mean (
Earley, Bernadette   +3 more
core  

The UK's Global Health Respiratory Network: Improving respiratory health of the world's poorest through research collaborations. [PDF]

open access: yes, 2019
Respiratory disorders are responsible for considerable morbidity, health care utilisation, societal costs and approximately one in five deaths worldwide [1-4].
Adab, P   +31 more
core   +9 more sources

The association between environmental tobacco smoke exposure and childhood respiratory disease: a review

open access: yesExpert Review of Respiratory Medicine, 2017
Introduction: Childhood respiratory illness is a major cause of morbidity and mortality particularly in low and middle-income countries. Environmental tobacco smoke (ETS) exposure is a recognised risk factor for both acute and chronic respiratory illness.
A. Vanker, R. Gie, H. Zar
semanticscholar   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Rituximab induced sympathetic crashing acute pulmonary oedema in a patient with interstitial lung disease: a rare and lifethreatening complication

open access: yesAsian Journal of Internal Medicine
Rituximab is a monoclonal antibody widely used to treat autoimmune diseases and haematologic malignancies. Although generally well tolerated, it can cause severe infusion-related reactions, including pulmonary complications.
K. Maduranga   +3 more
doaj   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini   +13 more
wiley   +1 more source

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