Results 141 to 150 of about 1,199,457 (266)

Current Clinical Perspectives of Biomarkers in Respiratory Diseases: A Narrative Review. [PDF]

J Clin Med
Gurajala S, Al Humoud SY, Al Yousif GF, Alameri RA, Pandurangam G, Fayyomi AKA, Abed S, Sardidi NS, Alrayes MM, Alsabhan TA, Alajmi SH, Alfaraj A, Al Ghannam N.   +12 more
europepmc   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Nature prescription for patients with chronic respiratory diseases. [PDF]

World Allergy Organ J
Urrutia-Pereira M, Solé D, Winders T, Martinez VR, Bueno RK, Pellegrini DDCP, Bueno JR, Derré Torres FH, Alberti CG, Marques BS, de Moraes BA, Sevá AC, Kaestner DB, Chong-Neto HJ, Haahtela T.   +14 more
europepmc   +1 more source

The Adolescent with Respiratory Disease

Journal of the Royal College of Physicians of London, 2000
openaire   +2 more sources

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Combating respiratory diseases with mucosal vaccines. [PDF]

J Virol
Tang PCH, Ling Z, Lee M, King NJC, Mahalingam S.   +4 more
europepmc   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

The respiratory microbiome influences the occurrence of respiratory diseases in children. [PDF]

Front Pediatr
Zheng K, Zhou SH, Liao S, Mu J, Han ZB, Wang B.   +5 more
europepmc   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

New Insights in Respiratory Diseases. [PDF]

Biomedicines
Bagnasco D, Bondi B.
europepmc   +1 more source