Results 41 to 50 of about 26,981 (283)
Phenotypic Expansion of Knobloch Syndrome Type 2 in an Individual With a De Novo PAK2 Variant
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT P21‐activated kinase 2 (PAK2) is a serine/threonine kinase essential for a variety of cellular processes including signal transduction, cellular survival, proliferation, and migration. A recent report proposed monoallelic PAK2 variants cause Knobloch syndrome type 2 (KNO2)—a developmental disorder primarily characterized by ocular anomalies ...
Elizabeth A. Werren +10 more
wiley +1 more source
Jurnal Ners dan Kebidanan IndonesiaBackground: Apart from increasing morbidity and motility, respiratory problems in newborn babies are a condition that can result in respiratory arrest and even death.
Febry Kusumawardhani +4 more
doaj +1 more source
Neonatal Respiratory Distress Secondary to Meconium Aspiration Syndrome
Children, 2021 Infants born through meconium-stained amniotic fluid (MSAF) are 100 times more likely than infants born through clear amniotic fluid to develop respiratory distress in the neonatal period.
Arielle L. Olicker +2 more
doaj +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT SETD2 has an essential role in epigenetic regulation. SETD2 pathogenic variants cause neurodevelopmental disorders (SETD2‐NDDs) that most commonly include various degrees of intellectual disability and behavioral disorders, macrocephaly, brain malformations, and generalized overgrowth.
Marie Lucain +11 more
wiley +1 more source
The Ultrasound Journal, 2023 Background Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a lethal neonatal lung disorder characterized by the decrease of the alveolar units, abnormalities in the air–blood barrier of the lung, and impaired gas exchange ...
Macarena L. Atun +2 more
doaj +1 more source
The role of surface charge in the interaction of nanoparticles with model pulmonary surfactants [PDF]
Soft Matter 14, 5764-5774 (2018), 2018 Inhaled nanoparticles traveling through the airways are able to reach the respiratory zone of the lungs. In such event, the incoming particles first enter in contact with the liquid lining the alveolar epithelium, the pulmonary surfactant. The pulmonary surfactant is composed of lipids and proteins that are assembled into large vesicular structures ...
arxiv +1 more source
Application of humanized mice in the safety experiments of antibody drugs
Animal Models and Experimental Medicine, EarlyView.The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun +9 more
wiley +1 more source
Бюллетень сибирской медицины, 2010 Respiratory distress syndrome of the newborn is a basic pathobiology immature infants and this grave condition of early neonatal period often is the cause of chronic lung disease — bronchopulmonary dysplasia (BPD).
Ye. B. Pavlinova +2 more
doaj +1 more source
Identifying ARDS using the Hierarchical Attention Network with Sentence Objectives Framework [PDF]
arXiv, 2021 Acute respiratory distress syndrome (ARDS) is a life-threatening condition that is often undiagnosed or diagnosed late. ARDS is especially prominent in those infected with COVID-19. We explore the automatic identification of ARDS indicators and confounding factors in free-text chest radiograph reports.
arxiv
Pharmacokinetics of betamethasone in pre‐eclampsia: An in vivo and ex vivo study
British Journal of Clinical Pharmacology, EarlyView.Aims To enhance understanding of betamethasone and its metabolites' pharmacokinetics in pregnancy, specifically early‐onset pre‐eclampsia, through a population pharmacokinetic model. Additionally, to investigate the placental metabolism and transfer of betamethasone and its main metabolites.
Sam Schoenmakers +15 more
wiley +1 more source