Results 51 to 60 of about 2,254,588 (283)

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Recruitment manoeuvres in acute respiratory distress syndrome: Little evidence for routine use [PDF]

, 2013
Acutely injured lungs consist of heterogeneous regions of aerated and collapsed alveoli. Implementation of alveolar recruitment manoeuvres (RMs) for the management hypoxemic respiratory failure, however, has been controversial.
Oliver Poole
core  

Plasma Metabolites in Early Sepsis Identify Distinct Clusters Defined by Plasma Lipids

Critical Care Explorations, 2021
OBJECTIVES:. Unbiased global metabolomic profiling has not been used to identify distinct subclasses in patients with early sepsis and sepsis-associated acute respiratory distress syndrome.
Angela J. Rogers, MD, MPH, Aleksandra Leligdowicz, MD, PhD, Kévin Contrepois, PhD, Alejandra Jauregui, BSc, Kathryn Vessel, BSc, Thomas J. Deiss, BSc, Annika Belzer, BSc, Tom Liu, MD, Matthew Lippi, MD, MPH, Serena Ke, BSc, Erin Ross, BSc, Hanjing Zhou, MSc, Carolyn Hendrickson, MD, MAS, Antonio Gomez, MD, Pratik Sinha, MD, PhD, Kirsten N. Kangelaris, MD, Kathleen D. Liu, MD, PhD, Carolyn S. Calfee, MD, MAS, Michael A. Matthay, MD   +18 more
doaj   +1 more source

Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome [PDF]

Background In acute respiratory distress syndrome (ARDS), respiratory drive often differs among patients with similar clinical characteristics. Readily observable factors like acid–base state, oxygenation, mechanics, and sedation depth do
Loring, Stephen H., Dzierba, Amy L., Serra, Alexis L., Minus, Emily, Sarge, Todd, Beitler, Jeremy R., Padilla, Clarissa, Baedorf-Kassis, Elias, Goodspeed, Valerie M., Murn, Michael, Matthay, Michael A., Talmor, Daniel, Garcia, Ivan, Gong, Michelle N., Cook, Deborah   +14 more
core   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Prone position in acute respiratory distress syndrome

, 2002
In the last few years prone positioning has been used increasingly in the treatment of patients with acute respiratory distress syndrome (ARDS) and this manoeuvre is now considered a simple and safe method to improve oxygenation.
PELOSI, PAOLO PASQUALINO, BRAZZI L, L. Brazzi, P. Pelosi, GATTINONI L., Brazzi, Luca, L. Gattinoni   +6 more
core   +1 more source

MetaboSense: An Integrated Quantum Dot‐Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In‐Line Monitoring of Lung Metabolism During Ex Vivo Perfusion

Advanced Science, EarlyView.
MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant, Pouyan Keshavarz Motamed, Thomas Borrillo, Lielle Ronen, Gabriel Siebiger, Guillermo Garza, Hesam Abouali, Md Fahim Al Fattah, Ines Jaber, Dayan Ban, Marcelo Cypel, Mingyao Liu, Shaf Keshavjee, Andrew T. Sage, Mahla Poudineh   +14 more
wiley   +1 more source

Surveillance of severe acute respiratory syndrome (SARS) in the post-outbreak period. [PDF]

, 2005
INTRODUCTION: This retrospective one-month survey evaluated the practicality of post-severe acute respiratory syndrome (SARS) surveillance recommendations in previously SARS-affected countries, namely Singapore.
Leo, YS, Escudero, IHG, Chen, MI
core   +4 more sources

Adult respiratory distress syndrome [PDF]

The Annals of The Royal College of Surgeons of England, 2017
Adult respiratory distress syndrome (ARDS) has now been described as a sequela to such diverse conditions as burns, amniotic fluid embolism, acute pancreatitis, trauma, sepsis and damage as a result of elective surgery in general. Patients with ARDS require immediate intubation, with the average patient now being ventilated for between 8 and 11 days.
S, Cutts, R, Talboys, C, Paspula, E M, Prempeh, R, Fanous, D, Ail   +5 more
openaire   +2 more sources

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source