Results 211 to 220 of about 4,036,807 (330)

Ventilation-induced acute kidney injury in acute respiratory failure: Do PEEP levels matter? [PDF]

open access: yesCrit Care
Benites MH   +4 more
europepmc   +1 more source

High Respiratory Drive and Excessive Respiratory Efforts Predict Relapse of Respiratory Failure in Critically Ill Patients with COVID-19

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2020
P. Esnault   +10 more
semanticscholar   +1 more source

A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis

open access: yesAdvanced Science, EarlyView.
The dynamic interplay between central respiratory chemoreceptors and the respiratory central pattern generator is essential for maintaining stable respiratory rhythm and patterns, particularly during sleep. This study offers novel insights into the anatomical, molecular, and functional characteristics of a medullary network involving the nucleus ...
Tianjiao Deng   +16 more
wiley   +1 more source

Factors Affecting the Length of Hospital Stay in Hypercapnic Respiratory Failure. [PDF]

open access: yesDiagnostics (Basel)
Ari M   +6 more
europepmc   +1 more source

Machine Learning‐Enabled Drug‐Induced Toxicity Prediction

open access: yesAdvanced Science, EarlyView.
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai   +5 more
wiley   +1 more source

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao   +19 more
wiley   +1 more source

Representation of Hispanic Patients in Clinical Trials for Respiratory Failure: A Systematic Review. [PDF]

open access: yesCrit Care Explor
Harlan EA   +10 more
europepmc   +1 more source

ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease

open access: yesAdvanced Science, EarlyView.
ADAR1‐HNRNPL interaction‐repressed circCANX recruits P53 mRNA and UPF1 to assemble a complex in nuclear. This complex promotes P53 mRNA degradation through the NMD pathway, and finally reduces autophagy and stress granules formation to further regulate inflammation.
Ting‐Ting Chen   +10 more
wiley   +1 more source

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