Results 241 to 250 of about 4,787,434 (307)

The Evolving Role of Extracorporeal Carbon Dioxide Removal in Acute Respiratory Failure: A Narrative Review. [PDF]

Cureus
Sherrin S, Kaur J, Taneja V, Mustafa W, Garg K, Kunal K.   +5 more
europepmc   +1 more source

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

Advanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou, Xiaolin Sun, Chengyu Liu, Yujia Shi, Meiqi Li, Meng Bo, Jingjie Zhai, Chunyan Li, Zhennan Wu, Xue Bai, Lin Wang   +10 more
wiley   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source

DHODH Drives Sunitinib Resistance Via a Non‐Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC

Advanced Science, EarlyView.
This non‑enzymatic function of DHODH drives sunitinib resistance by competing with TRIM37 to block TRIM28 ubiquitination, thereby stabilizing TRIM28 and activating VEGFA transcription. Disrupting the DHODH–TRIM28 interaction with lisaftoclax restores drug sensitivity.
Shijie Qian, Shihang Pu, Zhipeng Xu, Yiheng Ding, Ling Jin, Baochao Li, Qi Li, Xiaohai Xi, Zengjun Wang, Jiajun Xing, Aiming Xu   +10 more
wiley   +1 more source

Reply to: Diaphragm excursion and diaphragm thickening fraction: commonality and conflict

European Respiratory Review
Diego Poddighe, Alexandros Kalkanis, Dries Testelmans, Greet Hermans, Daniel Langer, on behalf of all authors of “Respiratory muscle dysfunction in acute and chronic respiratory failure: how to diagnose and how to treat?”   +5 more
doaj   +1 more source

Patients' Experiences of Care During Hospitalization for Acute Respiratory Failure During COVID-19: A Multi-Center Qualitative Study. [PDF]

J Patient Exp
Jung YEG, Golden SE, Maxcy C, Hope AA, Hauschildt K, Valley TS, Wolwowicz E, Sarma N, Hough CL, Vranas KC.   +9 more
europepmc   +1 more source

Renin-dependent association between oxidative stress and organ dysfunction in acute hypoxemic respiratory failure. [PDF]

J Anesth Analg Crit Care
Eleuteri D, Cutuli SL, Antonelli M, Montini L.   +3 more
europepmc   +1 more source

Vertical Displacement Index and Early Treatment-Related Physiological Improvement in Acute Respiratory Failure: An Exploratory Ultrasound-Based Study. [PDF]

Adv Respir Med
Sönmez BM, Şirin İ, Akçay G, Özdemir M, Güner NG.   +4 more
europepmc   +1 more source

Effectiveness of taking sequential mechanical ventilation in AECOPD with respiratory failure and risk factors for treatment failure. [PDF]

Front Med (Lausanne)
Xu R, Liu H, Liu Y, Mao C.
europepmc   +1 more source

Minimally invasive extracorporeal CO₂ removal in hypercapnic respiratory failure: a prospective observational study. [PDF]

Crit Care
Kryvenko V, Husain-Syed F, Schnell E, Oruqaj G, Morty RE, Herold S, Hecker M, Tello K, Seeger W, Vadász I.   +9 more
europepmc   +1 more source