Results 51 to 60 of about 32,467 (248)

Determination of the Primary Molecular Target of 1,2,4-Triazole-Ciprofloxacin Hybrids [PDF]

, 2015
We have synthesized and examined the antibacterial activity, toxicity and affinity towards bacterial type II topoisomerases of a series of 1,2,4-triazole-ciprofloxacin hybrids.
Agata Paneth, Aleksandra Strzelczyk, Anna Malm, Barbara Kaproń, Barbara Rajtar, Dalhoff, Małgorzata Polz-Dacewicz, Oliphant, Paweł Stączek, Sharma, Tomasz Plech, Urszula Kosikowska, Łukasz Świątek   +12 more
core   +2 more sources

Does the adoption of EUCAST susceptibility breakpoints affect the selection of antimicrobials to treat acute community-acquired respiratory tract infections? [PDF]

, 2012
Background: In several European Countries, by the end of 2012, CLSI guidelines will be replaced by EUCAST. We compared antimicrobial susceptibility results of a large number of respiratory pathogens using both EUCAST and previously adopted CLSI criteria ...
Barbieri, Ramona, Bassetti, Matteo, Debbia, Eugenio, Esposito, Susanna, Marchese, Anna   +4 more
core   +2 more sources

Ingestion of Milk Containing Very Low Concentration of Antimicrobials: Longitudinal Effect on Fecal Microbiota Composition in Preweaned Calves. [PDF]

, 2016
Although antimicrobial drugs are central to combat disease in modern medicine, the use of these drugs can have undesired consequences for human and animal health.
Bicalho, Rodrigo Carvalho, Foditsch, Carla, Lima, Svetlana, Siler, Julie D, Van Vleck Pereira, Richard, Warnick, Lorin D   +5 more
core   +13 more sources

Prevalence and Antimicrobial Susceptibility of Bovine Mycoplasma Species in Egypt

Biology, 2022
Among many bovine Mycoplasma species (spp.), Mycoplasma bovis is recognized as a significant causative agent of respiratory diseases in cattle. In recent years, resistant M. bovis isolates, especially to fluoroquinolones, have been reported globally as a
Ahmed M. Ammar, Marwa I. Abd El-Hamid, Yousreya H. Mohamed, Heba M. Mohamed, Dalal H. M. Al-khalifah, Wael N. Hozzein, Samy Selim, Wafaa M. El-Neshwy, Rania M. S. El-Malt   +8 more
doaj   +1 more source

Drug-Resistant Tuberculosis--Current Dilemmas, Unanswered Questions, Challenges and Priority Needs [PDF]

, 2012
Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short course (DOTS), a cost-effective strategy to contain the tuberculosis ...
Abubakar, Ibrahim, Atun, Rifat, Chakaya, Jeremiah, Cox, Helen, Ditiu, Lucica, Ford, Nathan, Grobusch, Martin, Hoelscher, Michael, Lawn, Stephen D., Maeurer, Markus, Marais, Ben, Mchugh, Timothy D., McNerney, Ruth, Memish, Ziad, Migliori, Giovanni-Battista, Mwaba, Peter, O'Grady, Justin, Pletschette, Michel, Ramsay, Andrew, Raviglione, Mario, Schito, Marco, Squire, S. Bertel, Swaminathan, Soumya, Zumla, Alimuddin   +23 more
core   +1 more source

Trends in yearly prevalence of third-generation cephalosporin and fluoroquinolone resistant Enterobacteriaceae infections and antimicrobial use in Spanish hospitals, Spain, 1999 to 2010 [PDF]

, 2011
Escherichia coli, Klebsiella pneumoniae, and Enterobacter spp. are a major cause of infections in hospitalised patients. The aim of our study was to evaluate rates and trends of resistance to third-generation cephalosporins and fluoroquinolones in ...
Asensio, A., Bishopberger, C., Calbo-Torrecillas, T., Campayo, J., Canton, R., Fernández-Crehuet, J., Hernández Navarrete, M.J., Ramos, A., Vaque-Rafart, J., Álvarez-Espejo, T.   +9 more
core   +2 more sources

In vitro activity of fluoroquinolones against common respiratory pathogens

West Indian Medical Journal, 2006
The treatment of respiratory infections is often empiric, necessitating the use of agents with a broad range of antimicrobial activity. The fluoroquinolones, having activity against common respiratory pathogens, fit this description. New fluoroquinolones have been developed in an attempt to improve the in vitro activity against a wide variety of ...
Tunger, A., Cilli, F., Aydemir, S.
openaire   +3 more sources

Emerging Mechanisms of Fluoroquinolone Resistance

Emerging Infectious Diseases, 2001
Broad use of fluoroquinolones has been followed by emergence of resistance, which has been due mainly to chromosomal mutations in genes encoding the subunits of the drugs' target enzymes, DNA gyrase and topoisomerase IV, and in genes that affect the ...
David C. Hooper
doaj   +1 more source

Results of A Local Combination Therapy Antibiogram For \u3cem\u3ePseudomonas Aeruginosa\u3c/em\u3e Isolates: Is Double Worth The Trouble? [PDF]

, 2017
Purpose: To determine the frequency at which fluoroquinolones and aminoglycosides demonstrate in vitro activity against non-urinary, non-skin/skin structure Pseudomonas aeruginosa isolates exhibiting decreased susceptibilities to one or more β-lactam ...
Davis, Jim, Dilworth, Thomas J., Elshaboury, Ramy, Munson, Erik, Song, Matthew   +4 more
core   +1 more source

Medicare Part D and Hospital Admissions due to Antimicrobial Resistance

Health Economics, EarlyView.
ABSTRACT Antimicrobial resistance (AMR) has been increasing rapidly in the United States despite government efforts to contain its spread. Both under‐utilization and overuse of prescribed antimicrobials contribute to rising resistance. The introduction of Medicare Part D in 2006 expanded prescription drug coverage for the elderly, including coverage ...
Ricardo B. Ang III
wiley   +1 more source