Results 91 to 100 of about 955,664 (289)

The prevalence of aspirin hypersensitivity in patients with nasal polyposis and contributing factors

, 2011
Background: Aspirin (acetylsalicylic acid [ASA]) hypersensitivity is frequent in patients with nasal polyps (NPs) and is called aspirin exacerbated respiratory disease, previously known as Samter's syndrome.
Korkmaz, Hakan, BAVBEK, SEVİM, Karasoy, DURU, Dursun, Berna, Dursun, Engin, Karasoy, Durdu Sertkaya   +5 more
core   +1 more source

Nerandomilast and the Evolving Therapeutic Paradigm in Pulmonary Fibrosis: From Mechanism to Clinical Efficacy

iNew Medicine, EarlyView.
Therapeutic mechanism, clinical efficacy and future directions for nerandomilast in pulmonary fibrosis. ABSTRACT The recent Phase III FIBRONEER trials establish nerandomilast, a novel oral phosphodiesterase 4B (PDE4B) inhibitor, as an effective therapy for idiopathic and progressive pulmonary fibrosis. By elevating cyclic adenosine monophosphate (cAMP),
Qianwen Bai, Jia Deng, Hongquan Wang, Yao Yao, Tao Wang   +4 more
wiley   +1 more source

Hypersensitivity pneumonitis: an overlooked cause of cough and dyspnea

Journal of Community Hospital Internal Medicine Perspectives, 2017
Hypersensitivity pneumonitis (HP) is an immune-mediated pulmonary disorder involving inflammation of the lung interstitium, terminal bronchioles, and alveoli caused by the immune response to the inhalation of an offending environmental airborne agent. It
Ryan S. D’souza, Anthony Donato
doaj   +1 more source

Protective Effects of Imeglimin Against Oxaliplatin‐Induced Peripheral Neurotoxicity: Evidence From In Vitro and In Vivo Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura, Kano Kinjo, Keisuke Mine, Yusuke Mori, Mami Ueda, Risa Kaneko, Yuna Kamiya, Taiga Sonoda, Haruka Mimata, Shunsuke Fujita, Takehiro Kawashiri, Daisuke Kobayashi   +11 more
wiley   +1 more source

Hypersensitivity reactions to intravenous antibiotics in cystic fibrosis [PDF]

, 2018
Hypersensitivity reactions to intravenous antibiotics are common in cystic fibrosis (CF). As well as causing immediate morbidity, the need for future avoidance of the causative antibiotic can have a long-term negative impact on CF management.
Andrew Bush, Carr, Siobhan B, Siobhan B Carr, Bush, Andrew, Marie F.A. Wright, Wright, Marie FA   +5 more
core   +1 more source

Sublingual Zolpidem for MRI in Claustrophobic Patients: A Prospective, Non‐Randomized Noninferiority Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Claustrophobia during MRI may lead to examination interruption, motion artifacts, prolonged acquisition time, and reduced diagnostic quality, frequently requiring intravenous sedation to ensure successful examination completion and adequate image acquisition.
Beatriz Birelli do Nascimento, Fernando de Sá Del Fiol, Marcus Vinicius Birelli do Nascimento, Lucas Bueno de Oliveira, Samanta Aparecida Alves, Lucas do Nascimento Bernardes   +5 more
wiley   +1 more source

Periodontitis and gastric disorders: Systematic review and meta‐analysis of functional dyspepsia and Helicobacter pylori gastritis

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis has been associated with other systemic inflammatory diseases, such as cardiovascular disease, diabetes mellitus, and rheumatoid arthritis; through the translocation of oral bacteria and local inflammatory mediators systemically.
Hadeel Mohammed Abbood, Jasim Mohammed Abbood, Ekin Yay‐Kus, Iain L. C. Chapple   +3 more
wiley   +1 more source

Respiratory Klebsiella pneumoniae infection transiently alters neutrophil responsiveness and enhances distal allergic inflammation

Frontiers in Immunology
BackgroundMicrobial exposure at respiratory interfaces shapes host defense, but whether prior localized bacterial infection can alter innate immune responsiveness and modulate subsequent allergic inflammation at distal sites remains unclear.
Xilan Xiao, Xilan Xiao, Jing Li, Jing Li, Tongqian Wu, Shirong Yan, Shirong Yan, Yan Wang, Rongtao Yang, Rongtao Yang, Ziqian Guo, Wengui Gong, Zhicheng Hu, Zhicheng Hu, Fang Yu, Fang Yu   +15 more
doaj   +1 more source

Phenytoin-induced acute hypersensitivity pneumonitis

Lung India, 2015
Lungs are target organs for toxic effects of various drugs due to many reasons. Diphenylhydantoin (DPH) is reported to have many extrapulmonary side effects. We are presenting a case of acute hypersensitivity pneumonitis (HP) secondary to DPH, presenting
Pallavi Periwal, Sharad Joshi, Rajesh Gothi, Deepak Talwar   +3 more
doaj   +1 more source

Fatal hypersensitivity pneumonitis associated with docetaxel

, 2013
We present a patient with advanced breast cancer treated with three cycles of docetaxel who developed repeated episodes of hypersensitivity pneumonitis, progressed to respiratory failure and death despite treatment with corticosteroids and supportive ...
Carl T McGary, Murali Krishna Gurram, Swaroopa Pulivarthi   +2 more
core   +1 more source