Results 211 to 220 of about 1,301,860 (307)

GABAB receptor‐mediated modulation of sensory neuron excitability: Roles of CaV2.2, G‐protein‐coupled inwardly rectifying potassium (GIRK) channels, and hyperpolarisation‐activated cyclic nucleotide‐gated (HCN) channels in human and mouse nociception

open access: yesExperimental Physiology, EarlyView.
Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela   +4 more
wiley   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker   +2 more
wiley   +1 more source

Severe angioedema requiring airway intervention following evolocumab administration: a case report. [PDF]

open access: yesAm J Cardiovasc Dis
Mojahedi A   +5 more
europepmc   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil   +11 more
wiley   +1 more source

Successful re-administration after nano-liposomal irinotecan-induced severe hypersensitivity reaction: a case report. [PDF]

open access: yesJ Pharm Health Care Sci
Kanno R   +5 more
europepmc   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise   +2 more
wiley   +1 more source

Heiner syndrome and correlation with food allergy<b>:</b> case report. [PDF]

open access: yesFront Allergy
Popovici P   +9 more
europepmc   +1 more source

Clinical Characteristics and Outcomes of Incomplete Cardia Reconstruction Cases Following Multiple Anti‐reflux Mucosectomy/Anti‐reflux Mucosal Ablation Treatments

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Introduction Anti‐reflux mucosectomy (ARMS) and anti‐reflux mucosal ablation (ARMA) are novel endoscopic treatments for proton pump inhibitor or potassium‐competitive acid blocker‐refractory gastroesophageal reflux disease. These procedures induce scarring of the artificial ulcer at the gastric cardia, which tightens the enlarged cardiac ...
Ippei Tanaka   +8 more
wiley   +1 more source

Ocular Allergy Within the Framework of the EAACI Nomenclature of Allergic Diseases and Hypersensitivity Reactions. [PDF]

open access: yesAllergy Asthma Immunol Res
Bogacka E   +7 more
europepmc   +1 more source

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