Results 181 to 190 of about 1,055,922 (317)

School absenteeism data for surveillance purposes: a proxy for acute respiratory infection rates. [PDF]

BMC Public Health
de Korne CM, Hooiveld M, van Hoek AJ, Bruijning-Verhagen PCJL.   +3 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Evaluating the Impact of Filmarray Pneumonia Plus Panel in Therapeutic Decision-Making in Critical Patients with Suspected Respiratory Infection. [PDF]

Antibiotics (Basel)
Latorre Ibars R, Carvalho-Brugger S, Rodríguez Ibáñez P, Vallverdú Vidal M, Iglesias Moles S, Miralbés Torner M, Bellés Bellés A, Castellano A, Campi D, Caballero J, Trujillano Cabello JJ.   +10 more
europepmc   +1 more source

Machine‐Learning Microfluidic Minute‐Scale Microorganism Metrics Monitoring(M6)

Advanced Science, EarlyView.
ABSTRACT On‐site monitoring of microorganisms remains challenging because of low concentrations, strong background interference, and dynamic aerosol diffusion, particularly for aerosol‐transmitted pathogens. Here, we report a rapid detection platform that integrates a Puri‐focusing microfluidic chip, electrochemical impedance spectroscopy (EIS), and ...
Ning Yang, Jiahao Ding, Si Chen, Lijie Yan, Shichao Ding, Lavonda Li, Junyi Sun, Haodong Liu, Tongge Li, Ning Liu, Mingji Wei, Xiaoyong Zhu, Xiaobo Zou, Shouqi Yuan, Xingcai Zhang   +14 more
wiley   +1 more source

Underweight Status Amplifies Respiratory Infection Mortality in Diabetes: Findings From a Nationwide Cohort Study. [PDF]

J Cachexia Sarcopenia Muscle
Choe HJ, Do Han K, Park JH, Lee J, Kwak MK, Choi YM, Moon SJ, Hong EG.   +7 more
europepmc   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

The impact of time of day on the diagnostic performance of tests for asthma

ERJ Open Research
Ran Wang, Stephen J. Fowler, Robert Maidstone, Laura Healy, Sarah Drake, Lesley Lowe, Angela Simpson, Clare S. Murray, Hannah J. Durrington   +8 more
doaj   +1 more source

Do sociodemographic factors modify the association between antenatal care utilisation and acute respiratory infection among infants in Ethiopia? [PDF]

PLOS Glob Public Health
Asresie M, Fekadu G, Erbas B, Batra M.
europepmc   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

Enterovirus respiratory infection in adults: an overlooked clinical burden emerging in the post-pandemic era. [PDF]

Infez Med
Venturini S, Reffo I, Messina A, Del Fabro G, Zanus-Fortes A, Callegari A, Giovagnorio F, Negri C, Basaglia G, Corich L, Zuccon U.   +10 more
europepmc   +1 more source