Results 241 to 250 of about 2,363,330 (306)

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

open access: yesAdvanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun   +18 more
wiley   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang   +9 more
wiley   +1 more source

Urgent Care Stewardship for Glucocorticoid Overuse in Acute Respiratory Infections.

open access: yesJAMA Netw Open
Patel D   +15 more
europepmc   +1 more source

Causes and Seasonality of Upper Respiratory Infections in Adults in Lesotho (2021-2022) (CORIAL). [PDF]

open access: yesCan J Infect Dis Med Microbiol
Sass N   +14 more
europepmc   +1 more source

Intraspecific diversity of <i>Staphylococcus aureus</i> populations isolated from cystic fibrosis respiratory infections. [PDF]

open access: yesMicrobiol Spectr
Alexander AM   +6 more
europepmc   +1 more source

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