A nomogram for estimating baseline respiratory insufficiency in patients with amyotrophic lateral sclerosis [PDF]
Annals of MedicineObjectives To develop and validate a nomogram for estimating the risk of baseline respiratory insufficiency in patients with amyotrophic lateral sclerosis (ALS).
Huifen Wang +5 more
doaj +2 more sources
Delayed Respiratory Insufficiency and Extramuscular Abnormalities in Selenoprotein N-Related Myopathies [PDF]
Frontiers in Neurology, 2021 Background: Selenoprotein N-related myopathies (SEPN1-RMs) are a subset of congenital myopathies caused by mutations of Selenoprotein N gene (SELENON or SEPN1).
Shu Zhang +9 more
doaj +2 more sources
Association of Continuously Measured Vital Signs With Respiratory Insufficiency in Hospitalized COVID-19 Patients: Retrospective Cohort Study [PDF]
Interactive Journal of Medical Research, 2022 BackgroundContinuous monitoring of vital signs has the potential to assist in the recognition of deterioration of patients admitted to the general ward.
Harriet M R van Goor +5 more
doaj +2 more sources
Inhibition of ATR Reverses a Mitochondrial Respiratory Insufficiency [PDF]
Cells, 2022 Diseases that affect the mitochondrial electron transport chain (ETC) often manifest as threshold effect disorders, meaning patients only become symptomatic once a certain level of ETC dysfunction is reached.
Megan B. Borror +13 more
doaj +2 more sources
Progressive Respiratory Insufficiency in a Teenager with Diaphragmatic Hypomotility Due to a Novel Combination of Gliomedin Gene Variants [PDF]
Children, 2022 Lethal congenital contracture syndrome 11 (LCCS11) is a form of arthrogryposis multiplex congenita (AMC) which is associated with mutations in the gliomedin gene (GLDN) and has been known to be severely life-shortening, mainly due to respiratory ...
Benjamin Eurich +5 more
doaj +2 more sources
Validation of the Arabic Severe Respiratory Insufficiency Questionnaire [PDF]
BMC Pulmonary Medicine, 2021 Background/objectives Assessment of Health-Related Quality of Life (HRQL) in patients with chronic respiratory insufficiency requiring Home Mechanical Ventilation (HMV) requires a valid measurement tool.
Marwan F. Alawieh +5 more
doaj +2 more sources
Respiratory insufficiency in an infant with osteogenesis imperfecta [PDF]
Respiratory Medicine Case ReportsOsteogenesis imperfecta (OI) is a rare presentation in the pediatric population. Whilst orthopedic manifestations are well-publicised, the multiple respiratory complications and mechanisms of respiratory failure in more severe cases are less well ...
Adeline Yi Ling Lim, Ajay Kevat
doaj +2 more sources
Lipin1 as a therapeutic target for respiratory insufficiency of duchenne muscular dystrophy [PDF]
Frontiers in PhysiologyIn Duchenne muscular dystrophy (DMD), diaphragm muscle dysfunction results in respiratory insufficiency which is a leading cause of death in patients. Mutations to the dystrophin gene result in myocyte membrane instability, contributing to the structural
Alexandra Brown +6 more
doaj +2 more sources
Assessing Symptom Burden and Depression in Subjects With Chronic Respiratory Insufficiency [PDF]
Journal of Palliative Care, 2022 Juho Lehto +2 more
exaly +2 more sources
External flail chest stabilization; The simple, low-cost way [PDF]
Journal of Cardiovascular and Thoracic Research, 2021 Flail chest is a life-threatening clinical entity which can be complicated by respiratory insufficiency. Paradoxical motion of a part of chest wall is the basic cause to put the blame on.
Efstratios Apostolakis +3 more
doaj +1 more source