Results 201 to 210 of about 1,417,972 (365)

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

Biallelic FGF4 Variants Linked to Thoracic Dystrophy and Respiratory Insufficiency. [PDF]

Clin Genet
Watts LM, Kinning E, Latner DR, Johnston M, Patrick-Esteve J, Cooper GM, Twigg SRF, Pagnamenta AT, Taylor JC.   +8 more
europepmc   +1 more source

Successfully Managed Respiratory Insufficiency in a Patient with a Novel Pathogenic Variant of the BMPER Gene: A Case Report. [PDF]

Diagnostics (Basel), 2022
Park HE, Yoon JA, Shin YB.
europepmc   +1 more source

Respiratory insufficiency. Advances in diagnosis and treatment.1. Pathology and diagnosis.2. The diagnosis of respiratory insufficiency based on clinical symptoms.

, 1990
大塚 洋久
openalex   +2 more sources

‘Congenital peripheral neuropathy presenting as apnoea and respiratory insufficiency: spinal muscular atrophy with respiratory distress type 1 (SMARD1)’ [PDF]

, 2004
Richard Appleton, Christoph Hübner, Katja Grohmann, Raymonda Varon   +3 more
openalex   +1 more source

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

Advanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen, YuWei Zhou, LongXiang Sheng, FangYing Mai, YuXuan Ding, ShiRan Hong, JiaXin Wu, JiaKai Pi, GuangMei Yan, YiJun Huang, JingJing Duan, Xuefeng Hua, Wei Yin   +12 more
wiley   +1 more source

Acute post-operative respiratory insufficiency and diffuse alveolar haemorrhage in a young and healthy adult. [PDF]

Breathe (Sheff)
Verresen T, Ruttens D.
europepmc   +1 more source

Rare causes of respiratory insufficiency in newborns. [PDF]

Physiol Res, 2020
Brucknerová J, Babala J, Ujházy E, Mach M, Juránek I, Brucknerová I.   +5 more
europepmc   +1 more source

Two Cases of Respiratory Insufficiency Secondary to Pre-procedural Nerve Blocks for Upper Extremity Injuries. [PDF]

Cureus, 2021
Patel NJ, Jameson M, Leonard M, Burns B.
europepmc   +1 more source