Results 261 to 270 of about 1,417,972 (365)

Phase I Clinical Trial. Safety of Baricitinib to prevent respiratory insufficiency in oncohematological patients affected by Coronavirus Disease-19: BARCOVID19 study

, 2023
Sanz-Linares G, Mussetti A, Albasanz-Puig A, Salvador I, Sureda A, Gudiol C, Salazar R, Marin M, García M, Navarro V, Haba IDl, Coma E, Dura X, Fontanals S, Serrano G, Cruz C, Mañez R, Moreno-González G.   +17 more
europepmc   +1 more source

Mannan-binding lectin insufficiency in children with recurrent infections of the respiratory system

, 2004
Maciej Cedzyński, Janusz Szemraj, A. St. Świerzko, Leokadia Bąk‐Romaniszyn, Mirosław Banasik, Krzysztof Zeman, David C. Kilpatrick   +6 more
openalex   +2 more sources

Distal weakness with respiratory insufficiency caused by the m.8344A > G “MERRF” mutation

Neuromuscular Disorders, 2014
E. Blakely, C. Alston, B. Lecky, B. Chakrabarti, G. Falkous, D. Turnbull, Robert W. Taylor, G. Gorman   +7 more
semanticscholar   +1 more source

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

Advanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen   +7 more
wiley   +1 more source

LPS‐Induced Mitochondrial Damage via SLC41A1‐Mediated Magnesium Ion Efflux Leads to the Pyroptosis of Dental Stem Cells

Advanced Science, EarlyView.
Lipopolysaccharide induces upregulation of the magnesium (Mg2+) efflux transporter solute carrier family 41 member 1 in dental stem cells, leading to a decrease in intracellular Mg2+ concentration and promoting the binding of oligomycin sensitivity‐conferring protein and cyclophilinD.
Yuan Liu, Chenyu Song, Liyuan Zhang, Xue Han, Chaoyuan Li, Yanhong Yan, Ludan Xing, Mengting Si, Bo Yang, Lingyuan Cheng, Akimi Muramatsu, Beizhan Jiang   +11 more
wiley   +1 more source

A rare cause of respiratory insufficiency: case presentation

Open Medicine, 2014
Diaconu Camelia, Paraschiv Bianca, Lungu Răzvan, Bartoş Daniela   +3 more
doaj   +1 more source

Understanding Respiratory Restrictions as a Function of the Scoliotic Spinal Curve in Thoracic Insufficiency Syndrome: A 4D Dynamic MR Imaging Study [PDF]

, 2018
Jayaram K. Udupa, Yubing Tong, Anthony Capraro, Joseph M. McDonough, Oscar H. Mayer, Suzanne Ho, Paul Wileyto, Drew A. Torigian, Robert M. Campbell   +8 more
openalex   +1 more source

Risk factors and prognosis of critically ill cancer patients with postoperative acute respiratory insufficiency.

World Journal of Emergency Medicine, 2013
Xue-zhong Xing, Yong Gao, Hai-jun Wang, Quan-Hui Yang, Chu-lin Huang, S. Qu, Hao Zhang, Hao Wang, Qing-ling Xiao, K. Sun   +9 more
semanticscholar   +1 more source

Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics

Advanced Science, EarlyView.
Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan, Enikő Zakar‐Polyák, Anita Adami, Anna A. Abbas, Yogita Sharma, Raquel Garza, Jenny G. Johansson, Diahann A. M. Atacho, Éva Renner, Miklós Palkovits, Csaba Kerepesi, Johan Jakobsson, Karolina Pircs   +12 more
wiley   +1 more source

eIF4E Enriched Extracellular Vesicles Induce Immunosuppressive Macrophages through HMGCR‐Mediated Metabolic Rewiring

Advanced Science, EarlyView.
Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal, Minal Nenwani, Ishaque Pulikkal Kadamberi, Sudhir Kumar, Olamide Animasahun, Jasmine George, Shirng‐Wern Tsaih, Prachi Gupta, Mona Singh, Anjali Geethadevi, Chandrima Dey, Noah Meurs, Ajay Shankaran, Pradeep Chaluvally Raghavan, Deepak Nagrath, Sunila Pradeep   +15 more
wiley   +1 more source