Results 41 to 50 of about 225,734 (253)

Neurological damage in SARS-CoV-2 infections

open access: yesRevista de la Facultad de Medicina Humana, 2021
The current Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has severely impacted the economy and health care system in more than 180 countries around the world in an unprecedented event, which since its inception has resulted in ...
Jorge Arturo Vega-Fernández   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Particularities of respiratory manifestations of COVID-19 infection in children

open access: yesOne Health & Risk Management, 2022
Introduction. COVID-19 infection is common in the pediatric population, presenting a variety of respiratory manifestations and complications. Material and methods. The study included 64 children from the COVID-19 section, IMSP IMC, with a mean age of
Svetlana SCIUCA   +4 more
doaj   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

RESPIRATORY ACIDOSIS

open access: yesАктуальные проблемы теоретической и клинической медицины, 2022
Respiratory acidosis is characterized by an increase in the concentration in the blood [H+] due to the retention of CO2 in the body. Normally, 15,000-20,000 moles of CO2 are formed in the body per day.
N. V. Leontyeva
doaj  

Lupus and the Lungs: The Assessment and Management of Pulmonary Manifestations of Systemic Lupus Erythematosus

open access: yesFrontiers in Medicine, 2021
Pulmonary manifestations of systemic lupus erythematosus (SLE) are wide-ranging and debilitating in nature. Previous studies suggest that anywhere between 20 and 90% of patients with SLE will be troubled by some form of respiratory involvement throughout
Raj Amarnani   +6 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

RESPIRATORY MANIFESTATIONS OF CHRONIC GRANULOMATOUS DISEASE; A CLINICAL SURVEY OF PATIENTS FROM IRANIAN PRIMARY IMMUNODEFICIENCY REGISTRY

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2003
Chronic granulomatous disease represents a group of inherited disorders of phagocytic system wherein recurrent infections are seen at different sites especially in the respiratory system.
M. Movahedi   +13 more
doaj  

Acute pancreatitis following SARS-CoV-2 infection: A case report

open access: yesSAGE Open Medical Case Reports, 2023
The novel coronavirus 2019 (COVID-19) which is caused by severe acute respiratory syndrome coronavirus-2 was first reported from Wuhan, China in December 2019. Since then, it has caused global crisis and it still continues to be a Public Health Emergency
Ugyen Choden   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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