Results 111 to 120 of about 4,089,932 (351)
RATIONALE: New evidence is available examining the use of corticosteroids in sepsis, acute respiratory distress syndrome (ARDS) and community-acquired pneumonia (CAP), warranting a focused update of the 2017 guideline on critical illness-related ...
Dipayan Chaudhuri+23 more
semanticscholar +1 more source
Overdiagnosis in respiratory medicine [PDF]
Claudia C. Dobler, Paul P. Glasziou
openaire +3 more sources
Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague+8 more
wiley +1 more source
Tropical respiratory medicine. 3. Histoplasmosis and pulmonary involvement in the tropics. [PDF]
Stan Houston
openalex +1 more source
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao+5 more
wiley +1 more source
Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72
ABSTRACT Objective We investigated the effects of C9orf72 mutation carriership on peripheral nerve excitability in asymptomatic individuals from families with a history of C9orf72 amyotrophic lateral sclerosis (ALS) and patients. Methods We included 47 asymptomatic individuals from families with a history of C9orf72 ALS, of whom 23 were carriers (C9 ...
Diederik J. L. Stikvoort García+3 more
wiley +1 more source
Intranasal dexmedetomidine administration in clinically recommended doses has a small but important risk of causing catastrophic respiratory failure in the setting of preexisting severe respiratory workloads.
William E. Novotny+2 more
doaj +1 more source
The Diverse Neuromuscular Spectrum of VPS13A Disease
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger+16 more
wiley +1 more source
Metastatic Mediastinal Germ Cell Tumour: A Florid and Fulminant Presentation
A previously healthy teenager presented with acute respiratory distress and constitutional symptoms. Imaging revealed a mediastinal mass with multiple pulmonary nodules, and markedly elevated β‐HCG confirmed metastatic choriocarcinoma.
Zhong Xhen Khor
doaj +1 more source