Results 131 to 140 of about 4,606,217 (394)

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Essentials of Respiratory Medicine [PDF]

, 1988

openalex   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

Classification of Respiratory Diseases

Current Directions in Biomedical Engineering
Contactless measurement methods offer a novel approach to assessing respiratory parameters. This study investigates the feasibility of classifying chronic obstructive pulmonary disease, asthma, and healthy individuals using depth-based plethysmography ...
Wichum Felix, Wiede Christian, Seidl Karsten   +2 more
doaj   +1 more source

Expert Recommendations on the Diagnosis, Treatment, and Care of Post-COVID-19 Conditions for Primary Health Services: Guangdong Province [PDF]

Zhongguo quanke yixue
Post-COVID-19 condition is defined as the presence of symptoms that cannot be explained by other diagnoses, lasting for at least 2 months, occurring three months after a possible or confirmed SARS-CoV-2 infection.
Primary Healthcare and Health Education Committee of the Guangdong Provincial Health Management Association, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine
doaj   +1 more source

Respiratory Medicine Revision [PDF]

, 1987
JA Wedzicha
openalex   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Intranasal Dexmedetomidine Administration Precipitates Respiratory Failure in Child With Croup and Asthma

Clinical Case Reports
Intranasal dexmedetomidine administration in clinically recommended doses has a small but important risk of causing catastrophic respiratory failure in the setting of preexisting severe respiratory workloads.
William E. Novotny, Pam Fox, Dynita Haislip   +2 more
doaj   +1 more source

Tropical respiratory medicine. 3. Histoplasmosis and pulmonary involvement in the tropics. [PDF]

, 1994
Stan Houston
openalex   +1 more source

Overdiagnosis in respiratory medicine [PDF]

Respirology, 2019
Claudia C. Dobler, Paul P. Glasziou
openaire   +3 more sources