Results 41 to 50 of about 4,606,217 (394)

Relative bioavailability of a pediatric dispersible tablet and adult film‐coated tablet of macitentan in healthy volunteers

Pharmacology Research & Perspectives, 2020
To compare the pharmacokinetic (PK) properties of the pediatric dispersible tablet formulation of macitentan and the adult film‐coated tablet formulation of macitentan in healthy subjects.
Patricia N. Sidharta, Radka Štěpánová, Susanne Globig, Ivan Ulč, Dénes Csonka   +4 more
doaj   +1 more source

A Research Agenda for Precision Medicine in Sepsis and Acute Respiratory Distress Syndrome: An Official American Thoracic Society Research Statement

American Journal of Respiratory and Critical Care Medicine, 2021
Background: Precision medicine focuses on the identification of therapeutic strategies that are effective for a group of patients based on similar unifying characteristics.
F. Shah, N. Meyer, D. Angus, R. Awdish, É. Azoulay, C. Calfee, G. Clermont, A. Gordon, A. Kwizera, A. Leligdowicz, J. Marshall, C. Mikacenic, P. Sinha, B. Venkatesh, H. Wong, F. Zampieri, S. Yende   +16 more
semanticscholar   +1 more source

Expert Consensus on the Clinical Application of Oral Small-molecule Antiviral Drugs Against COVID-19

​​​​​​​​Infectious Diseases & Immunity
. Although COVID‑19 no longer constitutes a “public health emergency of international concern”, which still has being spreading around the world at a low level.
Society of Bacterial Infection and Resistance of Chinese Medical Association, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Wei Zhao   +1 more
doaj   +1 more source

Unravelling machine learning: insights in respiratory medicine

European Respiratory Journal, 2019
Machine learning is the brain of an artificial intelligence machine. We describe how it is performed and explore its current use in respiratory medicine.
E. Angelini, Simon Dahan, Anand Shah
semanticscholar   +1 more source

Developing a nomogram-based scoring model to estimate the risk of pulmonary embolism in respiratory department patients suspected of pulmonary embolisms

Frontiers in Medicine, 2023
ObjectivePulmonary embolisms (PE) are clinically challenging because of their high morbidity and mortality. This study aimed to create a nomogram to accurately predict the risk of PE in respiratory department patients in order to enhance their medical ...
Feng Lanfang, Ma Xu, Chen Jun, Zhao Jia, Li Wenchen, Jia Xinghua   +5 more
doaj   +1 more source

The importance of real-life research in respiratory medicine: manifesto of the Respiratory Effectiveness Group

European Respiratory Journal, 2019
Randomised controlled trials (RCTs) are universally considered as the gold standard for evaluating the efficacy of treatments. Their main strength is that, through randomisation, they avoid any major imbalance between compared groups: therefore, observed
N. Roche, A. Anzueto, Sinthia Bosnic Anticevich, A. Kaplan, M. Miravitlles, D. Ryan, Joan B. Soriano, O. Usmani, Nikolaos G. Papadopoulos, G. Canonica   +9 more
semanticscholar   +1 more source

Therapeutic Effects and Molecular Mechanisms of Bioactive Compounds Against Respiratory Diseases: Traditional Chinese Medicine Theory and High-Frequency Use

Frontiers in Pharmacology, 2021
Respiratory diseases, especially the pandemic of respiratory infectious diseases and refractory chronic lung diseases, remain a key clinical issue and research hot spot due to their high prevalence rates and poor prognosis.
Jing Wang, Qibiao Wu, Lucky Ding, Siyu Song, Yaxin Li, Li Shi, Tan Wang, Daqing Zhao, Zeyu Wang, Xiangyan Li   +9 more
semanticscholar   +1 more source

Necrotizing pneumonia and purulent meningitis caused by bloodstream infection of CA-MRSA in a child: A rare case report

Frontiers in Pediatrics, 2022
Case presentationWe report the case of a girl aged 2 years and 10 months who had fever for 2 days, vomiting, poor mental status for 1 day, and one episode of convulsions.Symptoms and signsThe patient experienced a rapid onset of symptoms with fever ...
Peng Li, Lizhong Dai, Ke Yuan, Chunlan Song, Yibing Cheng, Yu Jing, Na Chen, Junhao Cui, Yangji Wang, Shuqin Fu   +9 more
doaj   +1 more source

Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD [PDF]

, 2014
Dirkje S Postma,1 Nicolas Roche,2 Gene Colice,3 Elliot Israel,4 Richard J Martin,5 Willem MC van Aalderen,6 Jonathan Grigg,7 Anne Burden,8 Elizabeth V Hillyer,8 Julie von Ziegenweidt,8 Gokul Gopalan,9 David Price8,10 1University of Groningen, Department ...
Burden, A, Colice, G, Gopalan, G, Grigg, J, Hillyer, EV, Israel, E, Martin, RJ, Postma, DS, Price, D, Roche, N, van Aalderen, WMC, von Ziegenweidt, J   +11 more
core   +6 more sources

The 2019–2020 Novel Coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2) Pandemic: A Joint American College of Academic International Medicine-World Academic Council of Emergency Medicine Multidisciplinary COVID-19 Working Group Consensus Paper

Journal of Global Infectious Diseases, 2020
What started as a cluster of patients with a mysterious respiratory illness in Wuhan, China, in December 2019, was later determined to be coronavirus disease 2019 (COVID-19).
S. Stawicki, R. Jeanmonod, Andrew C. Miller, L. Paladino, D. Gaieski, A. Yaffee, A. De Wulf, Joydeep Grover, T. Papadimos, C. Bloem, S. Galwankar, V. Chauhan, M. Firstenberg, S. Di Somma, D. Jeanmonod, Sona M. Garg, V. Tucci, H. Anderson, Lateef Fatimah, T. Worlton, S. Dubhashi, Krystal Glaze, S. Sinha, Ijeoma N Opara, Vikas Yellapu, Dhanashree S. Kelkar, A. El-Menyar, Vimal Krishnan, S. Venkataramanaiah, Yan Leyfman, Hassan Saoud Al Thani, Prabath WB Nanayakkara, S. Nanda, E. Cioè‐Peña, Indrani Sardesai, S. Chandra, A. Munasinghe, Vibha Dutta, S. D. Dal Ponte, R. Izurieta, J. Asensio, M. Garg   +41 more
semanticscholar   +1 more source