Results 81 to 90 of about 4,606,217 (394)

Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome. [PDF]

, 2017
In the 50 years since acute respiratory distress syndrome (ARDS) was first described, substantial progress has been made in identifying the risk factors for and the pathogenic contributors to the syndrome and in characterising the protein expression ...
Calfee, Carolyn S, Meyer, Nuala J
core   +1 more source

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Respiratory medicine

, 2014
●. Upper respiratory infections are commonplace, especially in young people, and are often contagious; ●. Lower respiratory infections are often contagious and some are potentially fatal; ●. Asthma is common and may be life-threatening; ●. Chronic obstructive pulmonary disease is common and disabling; ●. Tuberculosis worldwide is an important infection,
openaire   +2 more sources

Monogenic diseases in respiratory medicine: Clinical perspectives

Pediatric Investigation, 2017
With the increasing awareness of genetics in respiratory medicine and improvements in molecular diagnostic techniques, many complicated and rare diseases in respiratory medicine can be diagnosed.
Yao Yao, K. Shen
semanticscholar   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

A current model for training a pulmonologist

Терапевтический архив, 2013
The paper gives data on the importance of the results of genomic and postgenomic studies and the wide practical introduction of up-to-date diagnostic imaging techniques for improving the scientific and practical branches of modern pulmonology.
A G Chuchalin
doaj  

Mechanism of Airway Remodeling Induced by Repeated Inhalation of Methacholine in a Mouse Model of Asthma [PDF]

, 2015
Background:Increased severity of asthma is contributed by airway tissue remodeling, which may be associated with chronic allergic inflammation. A recent study revealed the potential capacity of repeated bronchoconstriction, e.g.
Department Of Respiratory Medicine Dokkyo Medical University Koshigaya Hospital, Department Of Respiratory Medicine Dokkyo Medical University Koshigaya Hospital, Department Of Respiratory Medicine Dokkyo Medical University Koshigaya Hospital, Department Of Respiratory Medicine Dokkyo Medical University Koshigaya Hospital, Department Of Respiratory Medicine Dokkyo Medical University Koshigaya Hospital, Department Of Respiratory Medicine Dokkyo Medical University Koshigaya Hospital, Department Of Respiratory Medicine Dokkyo Medical University Koshigaya Hospital, Hideyuki Satoh, Hironori Sagara, Kentaro Nakano, Kumiya Sugiyama, Naoto Fueki, Ryosuke Souma, Yasutsugu Fukushima   +13 more
core   +1 more source

Systems Biology and Clinical Practice in Respiratory Medicine. The Twain Shall Meet.

American Journal of Respiratory and Critical Care Medicine, 2016
Respiratory diseases are highly complex, being driven by host-environment interactions and manifested by inflammatory, structural, and functional abnormalities that vary over time.
C. Thamrin, U. Frey, D. Kaminsky, H. Reddel, A. Seely, B. Suki, P. Sterk   +6 more
semanticscholar   +1 more source