Results 111 to 120 of about 144,351 (212)
Animal Models and Experimental Medicine, EarlyView.This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin +9 more
wiley +1 more source
Circadian modulation of microglial physiological processes and immune responses
Glia, Volume 71, Issue 2, Page 155-167, February 2023., 2023 Main Points Microglia are rhythmic cells with an oscillatory expression in clock genes, cytokines, and other microglial markers. Microglial circadian rhythms determine their physiological function and immune responses. Abstract Microglia is considered the central nervous system (CNS) resident macrophages that establish an innate immune response against
Mara A. Guzmán‐Ruiz +11 more
wiley +1 more source
The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs
Advanced NanoBiomed Research, EarlyView.Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He +11 more
wiley +1 more source
Practical parameter identifiability of respiratory mechanics in the extremely preterm infant [PDF]
arXivThe complexity of mathematical models describing respiratory mechanics has grown in recent years, however, parameter identifiability of such models has only been studied in the last decade in the context of observable data. This study investigates parameter identifiability of a nonlinear respiratory mechanics model tuned to the physiology of an ...
arxiv
Advanced NanoBiomed Research, EarlyView.Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska +2 more
wiley +1 more source
In Situ Construction of Flexible Low‐Dimensional van der Waals Material Photodetectors
Advanced Physics Research, EarlyView.This review summarizes the progress in directly constructing low‐dimensional van der Waals material photodetectors on flexible substrates, including developing low‐melting‐point materials, electron‐beam‐enabled crystallization, photonic crystallization, modified chemical vapor deposition, and pulsed‐laser deposition, with a keen eye on fundamental ...
Yu Chen +7 more
wiley +1 more source
Autism Research, EarlyView.ABSTRACT To identify the neurocognitive mechanisms underpinning the social difficulties that characterize autism, we performed functional magnetic resonance imaging on pairs of autistic and non‐autistic adults simultaneously whilst they interacted with one another on the iterated Ultimatum Game (iUG)—an interactive task that emulates the reciprocal ...
Kristína Czekóová +8 more
wiley +1 more source
Human Mutation, Volume 43, Issue 12, Page 1673-1705, December 2022., 2022 Abstract Loss‐of‐function variants in the ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) cause ENPP1 Deficiency, a rare disorder characterized by pathological calcification, neointimal proliferation, and impaired bone mineralization. The consequence of ENPP1 Deficiency is a broad range of age dependent symptoms and morbidities
Stephanie A. Mercurio +8 more
wiley +1 more source
Juvenile mucopolysaccharidosis plus disease caused by a missense mutation in VPS33A
Human Mutation, Volume 43, Issue 12, Page 2265-2278, December 2022., 2022 Abstract A rare and fatal disease resembling mucopolysaccharidosis in infants, is caused by impaired intracellular endocytic trafficking due to deficiency of core components of the intracellular membrane‐tethering protein complexes, HOPS, and CORVET. Whole exome sequencing identified a novel VPS33A mutation in a patient suffering from a variant form of
Elena V. Pavlova +11 more
wiley +1 more source
Biochemistry and Molecular Biology Education, EarlyView.Abstract Energy is a crosscutting concept in science, but college students often perceive a mismatch between how their biology and chemistry courses discuss the topic. The challenge of reconciling these disciplinary differences can promote faulty reasoning—for example, biology students often develop the incorrect idea that breaking bonds is exothermic ...
Mingyu Yang +3 more
wiley +1 more source