Results 121 to 130 of about 144,351 (212)

Study on the efficacy of compound porcine cerebroside and ganglioside injection in patients with ischemic stroke: A randomized, single‐center, open‐label, prospective study

open access: yesIbrain, EarlyView., 2023
Compound porcine perebroside and ganglioside injection (CPCGI) was used to treat ischemic stroke. However, there was no clinical evidence of low‐dose CPCGI. We conducted a clinical study to analyze whether the clinical results of low‐dose and standard‐dose CPCGI in patients with ischemic stroke were different.
Ya Chen   +8 more
wiley   +1 more source

A simple approach to biophysical profiling of blood cells in extranodal NK/T cell lymphoma patients using deep learning‐integrated image cytometry

open access: yesBMEMat, EarlyView.
We developed a deep learning‐integrated image cytometry technique to profile biophysical attributes of blood cells from ENKTL patients. We demonstrate specific changes in cell size, eccentricity, and refractive index during treatment in a label‐free manner.
Seongcheol Park   +8 more
wiley   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

open access: yesBMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan   +12 more
wiley   +1 more source

Charting the landscape of the environmental exposome

open access: yesiMeta, Volume 1, Issue 4, December 2022., 2022
We describe the biological and chemical components of the environmental exposomes in three major environmental matrices that are highly relevant to human and social‐economical health—air, soil, and water. We discuss how different exposome components can interact with each other. Finally, we propose a list of outstanding challenges to be tackled to push
Xin Wei   +6 more
wiley   +1 more source

RespEar: Earable-Based Robust Respiratory Rate Monitoring [PDF]

open access: yesarXiv
Respiratory rate (RR) monitoring is integral to understanding physical and mental health and tracking fitness. Existing studies have demonstrated the feasibility of RR monitoring under specific user conditions (e.g., while remaining still, or while breathing heavily).
arxiv  

The effect of sodium nitroprusside in scaffolds for synergetic gas‐photothermal therapy of osteosarcoma

open access: yesBMEMat, EarlyView.
The PCLA‐SNP scaffolds can produce photothermal agents in situ under ultraviolet radiation. Then, the scaffold can release nitric oxide gas spontaneously and generate hyperthermia under near‐infrared laser to enhance ablation of bone tumors. Furthermore, the calcium and iron ions released from PCLA‐SNP scaffolds can accelerate bone regeneration ...
Shaojie Dong   +9 more
wiley   +1 more source

Accounting for the geometry of the respiratory tract in viral infections [PDF]

open access: yesarXiv
Increasingly, experimentalists and modellers alike have come to recognise the important role of spatial structure in infection dynamics. Almost invariably, spatial computational models of viral infections - as with in vitro experimental systems - represent the tissue as wide and flat, which is often assumed to be representative of entire affected ...
arxiv  

Cuproplasia and cuproptosis, two sides of the coin

open access: yesCancer Communications, EarlyView.
Abstract Copper is an essential micronutrient in the human body, mainly acting as a crucial cofactor required for a wide range of physiological processes across nearly all cell types. Recent advances revealed that tumor cells seize copper to fulfill their rapid proliferation, metastasis, immune evasion, and so on by reprogramming the copper regulatory ...
Kaizhong Lu   +4 more
wiley   +1 more source

Advanced strategic constructions of diketopyrrolopyrrole derivatives‐based organic semiconducting phototheranostics

open access: yesInterdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023
This review specially focuses on the detailed elaboration and summary perspective of the design and application of diketopyrrolopyrrole derivatives‐based organic semiconducting phototheranostics. This paper may provide a new sight into diketopyrrolopyrrole derivatives for developing personalized theranostics, while opening the door to cancer ...
Bo Wang   +4 more
wiley   +1 more source

Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan   +13 more
wiley   +1 more source

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