Results 91 to 100 of about 1,910,679 (307)

Exercise-induced respiratory muscle work: Effects on blood flow, fatigue and performance [PDF]

open access: yes, 2008
This is the post print version of this article. The official published version can be obtained from the link below.In healthy subjects, heavy intensity endurance exercise places substantial demands on the respiratory muscles as breathing frequency ...
C.A. Harms   +8 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

A provisional survey of the interaction between net photosynthetic rate, respiratory rate, and thallus water content in some New Zealand cryptogams [PDF]

open access: yes, 1980
The effect of water content on photosynthetic and respiratory rates in eight lichen species and one bryophyte species were studied using an injection infrared gas analyser technique. All species snowed a strong relationship between net assimilation rate (
Brown, D.H.   +2 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Decision Trees for Predicting the Physiological Responses of Rabbits

open access: yesAnimals, 2019
The thermal environment inside a rabbit house affects the physiological responses and consequently the production of the animals. Thus, models are needed to assist rabbit producers in decision-making to maintain the production environment within the ...
Patrícia Ferreira Ponciano Ferraz   +6 more
doaj   +1 more source

Respiratory analysis system and method [PDF]

open access: yes, 1973
A system is described for monitoring the respiratory process in which the gas flow rate and the frequency of respiration and expiration cycles can be determined on a real time basis.
Liu, F. F.
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Heart Rate Monitoring During Different Lung Volume Phases Using Seismocardiography

open access: yes, 2018
Seismocardiography (SCG) is a non-invasive method that can be used for cardiac activity monitoring. This paper presents a new electrocardiogram (ECG) independent approach for estimating heart rate (HR) during low and high lung volume (LLV and HLV ...
Bomar, Andrew J   +3 more
core   +1 more source

Effect of Preventive Supplementation with Zinc and other Micronutrients on Non-Malarial Morbidity in Tanzanian Pre-School Children: A Randomized Trial. [PDF]

open access: yes, 2012
The efficacy of preventive zinc supplementation against diarrhea and respiratory illness may depend on simultaneous supplementation with other micronutrients.
Ayşe Y. Demir   +10 more
core   +5 more sources

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