Results 101 to 110 of about 1,910,679 (307)

The importance of respiratory rate monitoring [PDF]

open access: yesBritish Journal of Nursing, 2019
Respiratory rate measurement is regarded as a core nursing skill. Yet there are numerous recorded discrepancies in the monitoring and assessment of patients' respiratory rate. This article discusses the importance of respiration rate in terms of patient clinical outcomes, monitoring and documentation.
openaire   +3 more sources

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

The development of a model to describe the influence of temperature and relative humidity on respiration rate of prickly pear cactus stems in reduced O2 conditions [PDF]

open access: yes, 2010
Respiration rate (RO2) of prickly pear cactus stems (Opuntia spp.) was measured as a function of 4 temperature (T) and 6 relative humidity (RH) combinations for O2 partial pressures between 15 and 0.8 kPa, which were considered to support aerobic ...
Beaudry, R.M.   +4 more
core   +3 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

A cohort study of the effectiveness of influenza vaccine in older people, performed using the United Kingdom general practice research database.

open access: yes, 2004
BACKGROUND: The effectiveness of influenza vaccination against hospitalization and death can only ethically be assessed in observational studies. A concern is that individuals who are vaccinated are healthier than individuals who are not vaccinated ...
Cumberland, Phillippa   +5 more
core   +1 more source

Early high flow nasal cannula therapy in bronchiolitis, a prospective randomised control trial (protocol): A Paediatric Acute Respiratory Intervention Study (PARIS) [PDF]

open access: yes, 2015
Background Bronchiolitis imposes the largest health care burden on non-elective paediatric hospital admissions worldwide, with up to 15 % of cases requiring admission to intensive care.
Andreas Schibler   +13 more
core   +3 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Validation of CTmax Protocols Using Cased and Uncased \u3ci\u3ePycnopsyche Guttifer\u3c/i\u3e (Trichoptera: Limnephilidae) Larvae [PDF]

open access: yes, 2018
The critical thermal maximum (CTmax) of a northern Lower Michigan population of Pycnopsyche guttifer was determined using four rates of temperature increase (0.10, 0.33, 0.50, and 0.70oC per minute), and two case states (intact and removed).
Houghton, David C   +2 more
core   +2 more sources

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

Modeling of Immunosenescence and Risk of Death from Respiratory Infections: Evaluation of the Role of Antigenic Load and Population Heterogeneity [PDF]

open access: yes, 2017
It is well known that efficacy of immune functions declines with age. It results in an increase of severity and duration of respiratory infections and also in dramatic growth of risk of death due to these diseases after age 65.
Barbi, Elisabetta   +5 more
core   +1 more source

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