Reducing Antibiotic Use in Pediatric Upper Respiratory Infection: A Multifaceted Parent-Clinician Approach [PDF]
, 2017 The goal of this QI initiative was to decrease inappropriate antibiotic for the treatment of pediatric upper respiratory infection (URI) in the retail clinic setting. The approach included the use of a protocol to treat viral upper respiratory illness, a
Lucas, Sydnee H, DNP, APRN +1 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
An Inertial-Based Wearable System for Monitoring Vital Signs during Sleep
SensorsThis study explores the feasibility of a wearable system to monitor vital signs during sleep. The system incorporates five inertial measurement units (IMUs) located on the waist, the arms, and the legs.
Spyridon Kontaxis +5 more
doaj +1 more source
Technique for analyzing human respiratory process [PDF]
, 1970 Electronic system /MIRACLE 2/ places frequency and gas flow rate of the respiratory process within a common frame of reference to render them comparable and compatible with ''real clock time.'' Numerous measurements are accomplished accurately on a ...
Liu, F. F.
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Methods and systems for extracting venous pulsation and respiratory information from photoplethysmographs [PDF]
, 2019 A system and method for separating a venous component and an arterial component from a red signal and an infrared signal of a PPG sensor is provided.
Nourani, Mehrdad, Yousefi, Rasoul
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Respiratory rate assessment from photoplethysmographic imaging
2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2014 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology ...
Karlen, Walter; id_orcid0000-0001-8643-3074 +5 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Comparing the effect of using normal saline, N-acetyl cysteine and not using them in endotracheal tube suction on physiologic parameters and the amount of secretions in intubated patients under mechanical ventilation [PDF]
, 2014 Aims: Today a large number of patients hospitalized in Intensive Care Unit need mechanical ventilation via an artificial air way. Since these patients have endotracheal tube, endotracheal suctioning is necessary for increasing oxygenation, cleaning the ...
Akbaryan Deheki, N. +6 more
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Medical Devices for Measuring Respiratory Rate in Children: a Review [PDF]
, 2016 Respiratory rate is an important vital sign used for diagnosing illnesses in children as well as prioritising patient care. All children presenting acutely to hospital should have a respiratory rate measured as part of their initial and ongoing ...
Burke, Derek +9 more
core +2 more sources
The (human) respiratory rate at rest
Journal of Mathematical Biology, 2022 AbstractAll schoolchildren know how often they breathe, but even experts don’t know exactly why. The aim of this publication is to develop a model of the resting spontaneous breathing rate using physiological, physical and mathematical methods with the aid of the principle that evolution pushes physiology in a direction that is as economical as ...
openaire +3 more sources