Results 81 to 90 of about 826,835 (308)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

RESPIRATORY RESISTANCE [PDF]

Anesthesiology, 1969
Fisher A. B., DuBois A. B., Hyde R. W.   +2 more
openaire   +2 more sources

Changing Trends in Bacteriological Profile of Respiratory Isolates during Pre-COVID-19, COVID-19 and Post-COVID-19 Era: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The Coronavirus Disease-2019 (COVID-19) pandemic has exacerbated the global challenge of antibiotic resistance, particularly among respiratory pathogens.
Garima Mittal, Rajender Singh, Piyush Kumar Rai, Mani Bhushan Pant, Barnali Kakati   +4 more
doaj   +1 more source

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]

, 2012
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
A. Vabret, Abt, Arbour, Arbour, B. Nal, Bonavia, Caignard, Caignard, Callendret, Callow, Caux, Chapuis, Collins, de Swart, de Witte, Desforges, Desforges, Engelmayer, Esposito, F. Tangy, Ferlazzo, Gagneur, Geijtenbeek, Glew, H. Law, Hahm, Hamdorf, Herbst, Hoarau, J. Millet, Kramer, Kärber, Law, Legge, M. L. Albert, M. Mesel-Lemoine, MacDonald, Mahanty, Movassagh, Muller, N. Escriou, Nogueira, O'Doherty, Olweus, P.-O. Vidalain, Pacanowski, Piqueras, Rosenzwajg, Sallusto, Servet-Delprat, Servet-Delprat, Servet-Delprat, Sizun, Spearman, Spiegel, Thitithanyanont, Thornberry, V. Lorin, Vabret, Wang, Yang, Yeager   +61 more
core   +3 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

From Microbial Ecology to Clinical Challenges: The Respiratory Microbiome’s Role in Antibiotic Resistance

Pathogens
Antibiotic resistance represents a growing public health threat, with airborne drug-resistant strains being especially alarming due to their ease of transmission and association with severe respiratory infections.
Adelina-Gabriela Niculescu, Mihaela Magdalena Mitache, Alexandru Mihai Grumezescu, Mariana Carmen Chifiriuc, Mara Madalina Mihai, Monica Marilena Tantu, Ana Catalina Tantu, Loredana Gabriela Popa, Georgiana Alexandra Grigore, Roxana-Elena Cristian, Mircea Ioan Popa, Corneliu Ovidiu Vrancianu   +11 more
doaj   +1 more source

Optimal antimicrobial duration for common bacterial infections [PDF]

, 2019
Most antibiotic use in Australia arises from prescriptions in the community. The risk of antibiotic-related adverse events, including resistance, increases with longer treatment courses.
Daveson, Kathryn, Del Mar, Christopher B., Wilson, Heather L.   +2 more
core   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

The acetyltransferase CysE modulates virulence and drug resistance of Mycobacterium tuberculosis by interfering with oxidative stress responses

Communications Biology
Acetyltransferases play a crucial role in biological processes by modifying a variety of substrates. However, their roles in the virulence of Mycobacterium tuberculosis (M. tb) are poorly understood.
Lan-Yue Zhang, Han Yin, Ying-Chao Wang, Mei-Yi Yan, Chun-Liang Wang, Xue-Tian Shang, Wei-Yi Liu, Zi-Hui Li, Hong-Yan Jia, Zong-De Zhang, Chuan-Zhi Zhu, Li-Ping Pan, Yi-Cheng Sun   +12 more
doaj   +1 more source

Management of acute bronchitis in healthy adults. [PDF]

, 2004
Acute respiratory infections (ARIs) are the most common infections in humans, accounting for half of all acute conditions each year in the United States. Acute bronchitis episodes represent a significant portion of these illnesses.
Aagaard, Eva, Gonzales, Ralph
core