Results 41 to 50 of about 892,215 (229)

1,2‐propanediol reformulation improves tribromoethanol safety and reveals pontine GABRA1 enrichment as a candidate mechanistic correlate of anesthesia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study develops a reformulated tribromoethanol (TBE) anesthetic using 1,2‐propanediol as a solvent to overcome solvent‐related toxicity. The novel formulation demonstrates, cardiovascular stability, and survival in prolonged protocols. It provides potent, dose‐dependent anesthesia without strain or sex differences.
Xia Li   +3 more
wiley   +1 more source

Respiratory sinus arrhythmia as an index of vagal activity during stress in infants: respiratory influences and their control. [PDF]

open access: yesPLoS ONE, 2012
Respiratory sinus arrhythmia (RSA) is related to cardiac vagal outflow and the respiratory pattern. Prior infant studies have not systematically examined respiration rate and tidal volume influences on infant RSA or the extent to which infants' breathing
Thomas Ritz   +5 more
doaj   +1 more source

Exploring the early observations of parents supporting their children with school attendance problems (SAPs): A co‐produced study

open access: yesBritish Educational Research Journal, EarlyView.
Abstract School Attendance Problems (SAPs) represent a significant challenge requiring early identification and intervention. Current service provision often does not recognise early indicators that parents observe, creating gaps between when initial concerns are raised and formal support is provided.
Tereza Aidonopoulou‐Read   +4 more
wiley   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant   +17 more
wiley   +1 more source

Respiratory Sinus Arrhythmia Activity Predicts Internalizing and Externalizing Behaviors in Non-referred Boys

open access: yesFrontiers in Psychology, 2017
Atypical respiratory sinus arrhythmia (RSA), a biomarker of emotion dysregulation, is associated with both externalizing and internalizing behaviors. In addition, social adversity and gender may moderate this association.
Wei Zhang, Shawn E. Fagan, Yu Gao
doaj   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape   +3 more
wiley   +1 more source

Social Support and Resting Respiratory Sinus Arrhythmia

open access: yes
Social support is consistently related to better health (Oveis et al., 2009; Porges, 2007), and aspects of relationships with parents and friends are related to lower mortality and inflammation (Shor et al., 2013; Uchino et al., 2015).
Danny Rahal
core   +6 more sources

Feasibility of Spectral Analysis as a Tool in Nursing Research to Quantify Patterns of Respiration in Premature Infants

open access: yesInternational Journal of Pediatrics
Background. Respiratory difficulties are a common concern in preterm infants, and they can lead to long-term health problems. Few studies have investigated the use of spectral analysis as a biomarker to quantify respiration patterns in preterm infants ...
Khlood Bubshait   +2 more
doaj   +1 more source

Stress Resilience Assessment Based on Physiological Features in Selection of Air Traffic Controllers

open access: yesIEEE Access, 2019
Stress resilience is recognized as an important occupational prerequisite for air traffic controllers (ATCs). A system for input/output multimodal stress resilience assessment based on physiological features has been developed and applied in the ATC ...
Kresimir Cosic   +5 more
doaj   +1 more source

Respiratory sinus arrhythmia in new‐born infants. [PDF]

open access: yesThe Journal of Physiology, 1987
1. Ventilation was measured in eleven healthy term infants during both quiet and active sleep, using the trunk plethysmograph, and instantaneous heart rate was derived from the electrocardiogram. Variations in individual respiratory and cardiac cycles were compared in each sleep state, and cross‐correlations between ventilation and heart rate were used
openaire   +2 more sources

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