High incidence of multiple viral infections identified in upper respiratory tract infected children under three years of age in Shanghai, China. [PDF]
BACKGROUND: Upper respiratory tract infection (URTI) is a major reason for hospitalization in childhood. More than 80% of URTIs are viral. Etiological diagnosis of URTIs is important to make correct clinical decisions on treatment methods.
Guocui Zhang +5 more
doaj +1 more source
Antigenic Variation between Human Respiratory Syncytial Virus Isolates
Three hybridoma antibodies, prepared against the RSN-2 strain of human respiratory syncytial (RS) virus, have been used to identify antigenic variation between 41 isolates of RS virus collected from widely separated geographical regions over a period of 29 years.
H B, Gimenez +3 more
openaire +2 more sources
Respiratory antiviral immunity and immunobiotics: Beneficial effects on inflammation-coagulation interaction during influenza virus infection [PDF]
Influenza virus (IFV) is a major respiratory pathogen of global importance, and the cause of a high degree of morbidity and mortality, especially in high-risk populations such as infants, elderly, and immunocompromised hosts.
Alvarez, Gladis Susana +3 more
core +1 more source
ABSTRACT Acute chest syndrome (ACS) is one of the most common severe complications of sickle cell disease (SCD). In recent years, a major role of inflammation and innate immunity has been evidenced, but ACS pathophysiology remains incompletely understood, and therapeutic options are limited.
Slimane Allali +14 more
wiley +1 more source
Viral placentitis: morphological features and verification possibilities
This article describes the results of own observations of viral placentitis caused by parvovirus, human immunodeficiency virus, respiratory syncytial virus and Herpesviridae family viruses – herpes simplex virus types 1 and 2, cytomegalovirus and Epstein–
A. V. Kolobov, V. E. Karev
doaj +1 more source
Respiratory syncytial virus (RSV) and influenza are among the most important causes of severe respiratory disease worldwide. Despite the clinical need, barriers to developing reliably effective vaccines against these viruses have remained firmly in place
S. Ascough, S. Paterson, C. Chiu
semanticscholar +1 more source
ONCOLYTIC ACTIVITY OF HUMAN RESPIRATORY SYNCYTIAL VIRUS
Oncolytic viruses (OVs) are emerging as novel tools in cancer therapy. Oncolytic virotherapy offers an attractive therapeutic combination of tumor-specific killing and immune co-stimulation, therefore amplifying the host immune response against tumors.
D, Dahrizal +3 more
openaire +2 more sources
Animal models of human respiratory syncytial virus disease
Infection with the human pneumovirus pathogen, respiratory syncytial virus (hRSV), causes a wide spectrum of respiratory disease, notably among infants and the elderly. Laboratory animal studies permit detailed experimental modeling of hRSV disease and are therefore indispensable in the search for novel therapies and preventative strategies.
Reinout A, Bem +2 more
openaire +3 more sources
Modifiable risk factors associated with bronchiolitis [PDF]
Background: We sought to clarify possibly modifiable risk factors related to pollution responsible for acute bronchiolitis in hospitalized infants. Methods: For this observational study, we recruited 213 consecutive infants with bronchiolitis (cases ...
Alessandroni, Claudia +13 more
core +1 more source
Model evaluation of target product profiles of an infant vaccine against respiratory syncytial virus (RSV) in a developed country setting [PDF]
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract disease in children worldwide and is a significant cause of hospital admissions in young children in England.
Kinyanjui, Timothy +5 more
core +1 more source

