Results 151 to 160 of about 79,643 (236)

Gut Microbiota Colonization in Early Life Influences Susceptibility to Adulthood Hepatic Lipid Accumulation in High‐Fat‐Diet‐Fed Mice

Advanced Science, Volume 12, Issue 21, June 5, 2025.
This study indicates that perinatal antibiotic exposure elevates susceptibility to high‐fat‐diet‐induced hepatic lipid accumulation via disrupting early‐life gut microbiota colonization. The decreased Lactobacillus colonization inhibits primary‐to‐secondary bile acid conversion, lowering secondary bile acids, enhancing adulthood intestinal lipid ...
Yan‐Yan Zhu, Xin Dong, Hao Zhou, Ze‐Yan Li, Bo Wang, Ya‐Ping Song, Zhi‐Bing Liu, Xue Lu, Yi‐Hao Zhang, Yichao Huang, Hua Wang, De‐Xiang Xu   +11 more
wiley   +1 more source

Comparison of Perceived Adverse Events After COVID‐19 Vaccination Between Pregnant and NonPregnant Women Using Two Cohort Studies in the Netherlands

Birth Defects Research, Volume 117, Issue 6, June 2025.
ABSTRACT Background Maternal vaccines are upcoming. A clear picture of the adverse events (AEs) after maternal vaccination and whether this is comparable to a nonpregnant population is important. The objective of our study was to compare perceived AEs after COVID‐19 vaccination between pregnant and nonpregnant women and to study if it is feasible to ...
Petra J. Woestenberg, Annika W. Terpstra, Florence van Hunsel, Thomas Lieber, Veronique Y. F. Maas   +4 more
wiley   +1 more source

Postpandemic immunity debt of common cold in England: an interrupted time series study

International Journal of Infectious Diseases
This study investigates immunity debt in five common cold viruses (adenovirus, parainfluenza virus, human metapneumovirus, rhinovirus, and respiratory syncytial virus) in England using weekly positivity rate data from UKHSA.
Char Leung, Li Su
doaj  

Evaluating the Potential Adverse Effects of Favipiravir on Biochemical, Histopathological, and Spermatological Parameters in Male Rats' Testicular Tissue

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.
ABSTRACT Favipiravir is a selective RNA polymerase inhibitor and a broad‐spectrum antiviral drug. Favipiravir reduces cell proliferation by inhibiting RNA transcription, particularly in rapidly proliferating cells such as spermatogonia. The aim of this study was to investigate the effects and mechanism of action of favipiravir (T‐705) on sperm quality ...
Ali Doğan Ömür, Gamze Uçak, Adem Kara, Elif Erbaş, Serkan Ali Akarsu, Seçkin Özkanlar, Nevra Aydemir Celep   +6 more
wiley   +1 more source

Genetic and Inflammatory Signatures Associated With Worse Prognosis in Hospitalized Patients With Severe SARS‐CoV‐2 Infection With and Without Diabetes

Journal of Medical Virology, Volume 97, Issue 6, June 2025.
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SAR‐CoV‐2) presents with a diverse symptomology, ranging from asymptomatic to severe disease, but the mechanism of risk factors such as diabetes remains unelucidated. The current retrospective cohort study of 182 patients, with and without COVID‐19 and diabetes, analyzed leftover blood specimens
Marshall Yuan, Andrew Wassef, Davit Sargsyan, Vahe Nersisyan, Javier Cabrera, Ronald G. Nahass, Wael Hassan, Ah‐Ng Kong, Luigi Brunetti   +8 more
wiley   +1 more source

IL‐37 Mitigates the Inflammatory Response in Macrophages Induced by SARS‐CoV‐2 Omicron Infection Through the NF‐κB Signaling Pathway

MedComm, Volume 6, Issue 6, June 2025.
IL‐37 mitigates the infiltration of macrophages and suppresses the production of macrophage‐associated chemokines (such as CCL3 and CCL4) induced by SARS‐CoV‐2 Omicron infection through NF‐κB signaling pathway. ABSTRACT The expression levels of macrophage‐associated cytokines are significantly greater in COVID‐19 patients than in healthy individuals ...
Feifei Qi, Yiwei Yan, Mingya Liu, Qi Lv, Yanfeng Xu, Ming Liu, Fengdi Li, Ran Deng, Xujian Liang, Shuyue Li, Guocui Mou, Linlin Bao   +11 more
wiley   +1 more source

Diagnostic virology. [PDF]

, 1987
Diagnostic virology services are increasingly available and pertinent as the number of useful antiviral agents grows. In this article, current methods of diagnosis are reviewed with special emphasis on rapid procedures.
Drew, WL
core  

Nirsevimab immunisation of infants and respiratory syncytial virus (RSV)‐associated hospitalisations, Western Australia, 2024: a population‐based analysis

Medical Journal of Australia, EarlyView.
Lauren E Bloomfield, Nevada V Pingault, Rachel E Foong, Sarah French, Jo‐Anne Morgan, Ushma Wadia, Hannah C Moore, Christopher C Blyth, Peter C Richmond, Paul K Armstrong, Paul V Effler   +10 more
wiley   +1 more source

Phase Separation: A New Dimension to Understanding Tumor Biology and Therapy

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Liquid–liquid phase separation (LLPS) facilitates the assembly of biomolecular condensates by leveraging weak multivalent interactions. The low‐complexity domains, foldable domains of proteins, and nucleic acids provide multivalent interaction sites among different molecules and contribute to the formation of condensates.
Xingwen Wang, Minqiao Lu, Yi Zhang, Jiangwen Ma, Ying Hu   +4 more
wiley   +1 more source

Identification, validation, and characterization of approved and investigational drugs interfering with the SARS‐CoV‐2 endoribonuclease Nsp15

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Since the emergence of SARS‐CoV‐2 at the end of 2019, the virus has caused significant global health and economic disruptions. Despite the rapid development of antiviral vaccines and some approved treatments such as remdesivir and paxlovid, effective antiviral pharmacological treatments for COVID‐19 patients remain limited. This study explores
Spyros D. Chatziefthymiou, Maria Kuzikov, Sara Afandi, Greta Kovacs, Sukrit Srivastava, Andrea Zaliani, Andrey Gruzinov, Guillaume Pompidor, Michele Lunelli, Golam Rizvee Ahmed, Jörg Labahn, Johanna Hakanpää, Björn Windshügel, Michael Kolbe   +13 more
wiley   +1 more source