Results 81 to 90 of about 152,217 (292)

Human and bovine respiratory syncytial virus vaccine research and development [PDF]

, 2008
Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine, Meyer, Gilles, Schelcher, François   +2 more
core   +2 more sources

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Dynamics of the bacterially expressed conserved immunogenic region of the human respiratory syncytial virus G protein. [PDF]

, 2011
Despite all efforts, there is still no effective vaccine available against the human respiratory syncytial virus (HRSV) that is a major cause of severe lower respiratory tract disease in infants and the elderly.
Bembridge, Cann, Cano, Carrio, Collins, Collins, Crowe, Crowe, de Waal, Domachowske, Ejima, Fang, Godefroy, Hacking, Hancock, Harker, Harker, Leinweber, Levine, Li, Li, Mader, Melero, Miller, Murata, Olmsted, Peebles, Plotnicky-Gilquin, Power, Routledge, Sigurs, Simmons, Spinola, Stittelaar, Teng, Tripp, Vallejo, Zeng, Zeng   +38 more
core   +1 more source

Mucin‐Inspired Filamentous Sulfated Copolymers Effectively Inhibit Human Respiratory Syncytial Virus (hRSV) Infectivity

Advanced Science, EarlyView.
Virucidal polymers serve as effective antivirals by not only inhibiting viruses but also destroying them. Inspired by the chemical properties of mucin‐mimetics, dendronized polyglycerol‐sulfated, mucin‐inspired amphiphilic copolymers (MIACPs) have been developed.
Raju Bej, Enyu Xie, Kai Ludwig, Robert F. Schmidt, Yannic Kerkhoff, Robert Dalgliesh, Nilanjan Paul, Michael Gradzielski, Andreas Herrmann, Christian Sieben, Rainer Haag   +10 more
wiley   +1 more source

CX3CR1 as a respiratory syncytial virus receptor in pediatric human lung

Pediatric Research, 2019
Background Data on the host factors that contribute to infection of young children by respiratory syncytial virus (RSV) are limited. The human chemokine receptor, CX3CR1, has recently been implicated as an RSV receptor. Here we evaluate a role for CX3CR1
C. Anderson, Chinyi Chu, Qian Wang, Jared A. Mereness, Yue Ren, K. Donlon, S. Bhattacharya, Ravi S Misra, E. Walsh, Gloria S. Pryhuber, T. Mariani   +10 more
semanticscholar   +1 more source

Chlorogenic Compounds from Coffee Beans Exert Activity against Respiratory Viruses [PDF]

, 2016
Chlorogenic acids are secondary metabolites in diverse plants. Some chlorogenic acids extracted from traditional medicinal plants are known for their healing properties, e.g., against viral infections.
Benedetti, Fabio, Berti, Federico, Camps, Anita, Forzato, Cristina, Navarini, Luciano, Persoons, Leentje, Sinisi, Valentina, Stevaert, Annelies, Vermeire, Kurt   +8 more
core   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

A Single-Center Study of Viral Respiratory Tract Infections in Hospitalized Children From the Kurdistan Region of Iraq

Global Pediatric Health, 2018
Viral respiratory infections are among the most common causes of disease in humans, particularly in young children, and remain a major public health problem worldwide.
Dlshad A. Hassan PhD, Shwan K. Rachid PhD, John Ziebuhr MD   +2 more
doaj   +1 more source

Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection

Journal of Infectious Diseases, 2018
Using ferret models of influenza virus and human respiratory syncytial virus (hRSV), we demonstrate that infection with influenza virus can prevent or limit infection with hRSV, whereas infection with hRSV reduces morbidity attributed to influenza virus ...
K. Chan, Louise A. Carolan, D. Korenkov, J. Druce, J. McCaw, P. Reading, I. Barr, K. Laurie   +7 more
semanticscholar   +1 more source

Ultrafast Dense Immobilization of Noble Metal Nanoparticles on Customizable Multifunctional Polymer Microspheres for Heterogeneous Catalysis and Multiplexed Biodetection

Advanced Science, EarlyView.
This work proposes a facile co‐assembly strategy to achieve highly uniform and dense immobilization of diverse noble metal nanoparticles onto metastable multifunctional (e.g., magnetic or fluorescent) polymer microspheres, enabling fabrication of complex hierarchical superstructures.
Jie Zhao, Xinyi Liu, Dan Li, Xuefei Jing, Weijie Wu, Liangrui He, Yizhang Tang, Zhen Liu, Yulin Zeng, Haitian Sha, Huibin Qiu, Xujiang Yu, Wanwan Li   +12 more
wiley   +1 more source