Results 111 to 120 of about 265,748 (319)

Respiratory Syncytial Virus Infection

Journal of the Japanese Association for Infectious Diseases, 2005
Human respiratory syncytial virus (RSV) is the most common worldwide cause of lower respiratory tract infections (LRI) in infants less than 12 months of age. RSV isolates can be divided into group A and B. In addition, there were many genotypes within each group, and these genotypes have evolved global setting with temporal and geographic clustering ...
openaire   +4 more sources

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

British Journal of Clinical Pharmacology, EarlyView.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart, Emiel Leegwater, Thomas H. Ottens, Emile F. Schippers, Erik B. Wilms, David M. Burger, Cees van Nieuwkoop, Liesbeth B. E. Bosma   +7 more
wiley   +1 more source

Diagnostic and economic evaluation of a point-of-care test for respiratory syncytial virus

ERJ Open Research, 2020
Respiratory syncytial virus is a common cause of bronchiolitis. Historically, point-of-care tests have involved antigen detection technology with limited sensitivity.
A. Joy Allen, Andrea Gonzalez-Ciscar, Clare Lendrem, Jana Suklan, Karen Allen, Ashley Bell, Frances Baxter, Stephen Crulley, Louise Fairlie, Danielle Hardy, Louise Johnston, Joanne McKenna, Nicole Richards, Gavin Shovlin, Clare Simmister, Sheila Waugh, Philip Woodsford, Sara Graziadio, Michael Power, A. John Simpson, Prashant Kumar, Katherine Eastham, Malcolm Brodlie   +22 more
doaj   +1 more source

Bronchiolitis – It Is Time for a Unique Definition [PDF]

, 2016
Bronchiolitis is the most common lower respiratory tract infections in infants. It is time to reach a unique clinical definition, encompassing the acute onset of respiratory distress with cough, tachypnoea, retraction and
Midulla, Fabio, Nenna, Raffaella
core   +1 more source

Cryo-EM structure of the respiratory syncytial virus RNA polymerase

Nature Communications, 2020
The respiratory syncytial virus (RSV) RNA polymerase, constituted of a 250 kDa large (L) protein and tetrameric phosphoprotein (P), catalyzes three distinct enzymatic activities — nucleotide polymerization, cap addition, and cap methylation.
D. Cao, Yunrong Gao, Claire Roesler, Samantha Rice, P. D'Cunha, Lisa Zhuang, J. Slack, M. Domke, Anna Antonova, Sarah Romanelli, Shayon Keating, Gabriela Forero, Puneet Juneja, B. Liang   +13 more
semanticscholar   +1 more source

Population Pharmacokinetics of Clesrovimab in Preterm and Full‐Term Infants

Clinical Pharmacology &Therapeutics, EarlyView.
Clesrovimab is a half‐life extended monoclonal antibody targeting the respiratory syncytial virus fusion protein. Three studies (phase Ib/IIa [MK‐1654‐002], phase IIb/III [CLEVER], and phase III [SMART]) were conducted to evaluate the efficacy, safety, and pharmacokinetics (PK) of clesrovimab in infants.
Ziheng Hu, Farina Hellmann, Xiaowei Zang, Nele Plock, Keyur Parmar, Radha A. Railkar, S. Y. Amy Cheung, Brian M. Maas, Ferdous Gheyas   +8 more
wiley   +1 more source

Establishing presence of antibodies against bovine respiratory syncytial virus (BRSV), parainfluenza virus 3 (PI3) and bovine herpesvirus 1 (BHV 1) in blood serum of cattle using indirect immunoenzyme probe [PDF]

, 2009
A total of 92 samples of bovine blood serum were examined for the presence of antibodies against the bovine respiratory syncytial virus using indirect immunoenzyme probe - iELISA.
Dimitrijević Blagoje, Knežević Dejan, Milić Nenad, Nišavić Jakov, Radojičić Marina, Stojić Velibor, Vujanac Ivan, Šamanc Horea   +7 more
core   +1 more source

Expert consensus on palivizumab use for respiratory syncytial virus in developed countries.

Paediatric Respiratory Reviews, 2020
Respiratory syncytial virus (RSV) infection is a leading cause of hospitalisation in early childhood and palivizumab is the only licensed intervention for prevention.
M. Luna, P. Manzoni, B. Paes, E. Baraldi, V. Cossey, A. Kugelman, R. Chawla, A. Dotta, R. Rodríguez Fernández, B. Resch, X. Carbonell-Estrany   +10 more
semanticscholar   +1 more source

Curcuminoids amplify host innate antiviral immunity via the CRYAB‐RBM26 axis in viral infection

iMeta, EarlyView.
DMC/CUR antagonize viral hijacking of host nucleic acid resources and finely regulate the induction and effector phases of the type I interferon (IFN‐I) pathway through the CRYAB‐RBM26 axis. This molecular axis serves as a key downstream regulator for DMC/CUR activation of the IFN‐I pathway.
Tingting Chen, Xiang Wang, Guangyuan Zhang, Lu Wang, Junhao Wan, Lirong Tan, Xinyue Fan, Siqin Meng, Zhixing Jin, Yuzhang Liang, Haoze Li, Ziyuan Wan, Xiaotong Xu, Yan Zhang, Li Qin, Anna Malashicheva, Yu Du, Guangchao Zang, Guixue Wang   +18 more
wiley   +1 more source

Detection of Respiratory Syncytial Virus and Human Metapneumovirus in Children with Respiratory Tract Infection by Use Real Time Polymerase Chain Reaction

Diyala Journal of Medicine, 2018
  Background: Respiratory tract illness is a major cause of morbidity and mortality among children, elderly and immunocompromised patients worldwide.
Hala Luay Abduljabbar, Areej Atiyah Hussein, Iman M Aufi, Qasim Sharhan Al-Mayah   +3 more
doaj   +2 more sources