Results 121 to 130 of about 126,896 (285)

Single‐dose Pasteurella multocida and Histophilus somni autogenous vaccines administered at induction significantly improved feedlot cattle performance and profitability in Australia

Australian Veterinary Journal, EarlyView.
Background Bovine respiratory disease (BRD) is the most economically important disease affecting feedlot cattle. While viral pathogens are initiating agents, bacterial coinfections exacerbate disease severity. Vaccines for Pasteurella multocida and Histophilus somni are not commercially available in Australia.
GM Werid, T Batterham, L O'Meara, K Petrovski, WS Pitchford, DJ Trott   +5 more
wiley   +1 more source

Protectin D1 and maresin 1 attenuate airway hyperreactivity induced by IL‐13 in human isolated small bronchi

British Journal of Pharmacology, EarlyView.
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma, Sven‐Erik Dahlén, Craig E. Wheelock, Mikael Adner, Mamdoh Al‐Amerie, Erik Sachs, Kasra Vali Jalali, Leonardo De Maria, Henric Olsson, Jesper Säfholm   +9 more
wiley   +1 more source

Targeting Genome Maintenance Defects of Cancers Using Chain‐Terminating Nucleoside Analogs

Cancer Science, EarlyView.
Nucleoside analogs interfere with DNA replication either by their chain‐terminating properties or by serving as DNA damage on the template. The genome maintenance pathways required to maintain cellular tolerance to each nucleoside analog vary depending on the drug.
Ryotaro Kawasumi, Rubaiat E. Tabassum, Kouji Hirota   +2 more
wiley   +1 more source

The role of viral interaction in household transmission of symptomatic influenza and respiratory syncytial virus

Nature Communications
The role of viral interaction—where one virus enhances or inhibits infection with another virus—in respiratory virus transmission is not well characterized.
Jessica C. Ibiebele, Elie-Tino Godonou, Amy P. Callear, Matthew R. Smith, Rachel Truscon, Emileigh Johnson, Marisa C. Eisenberg, Adam S. Lauring, Arnold S. Monto, Sarah Cobey, Emily T. Martin   +10 more
doaj   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Risk and protective factors for meningococcal disease in adolescents: matched cohort study [PDF]

, 2006
Objective: To examine biological and social risk factors for meningococcal disease in adolescents. Design: Prospective, population based, matched cohort study with controls matched for age and sex in 1:1 matching.
Booth, C., Booy, R., Coen, P.G., Kaczmarski, E., Klein, N., Peckham, C., Stuart, J.M., Tully, J., Viner, R.M., Zambon, M.   +9 more
core  

Validation of the Scale for the Assessment of Illness Behavior (SAIB) in a community sample of elderly people.

, 2012
The aim of this study was to evaluate the construct validity of the SAIB in a community sample of elderly people. The SAIB was administered to a large community sample representative of the German population aged 60-85 years (n=1593).
Bhaskaran, K, Brähler, E, Engelberg, PM, Glaesmer, H, Singer, S   +4 more
core   +1 more source

Mass‐Standardised Differential Antibody Binding to a Spectrum of SARS‐CoV‐2 Variant Spike Proteins: Wuhan, Alpha, Beta, Gamma, Delta, Omicron BA.1, BA.4/5, BA.2.75 and BA.2.12.1 Variants—Antibody Immunity Endotypes

Immunology, EarlyView.
Fully quantitative, mass‐standardised, antibody responses to ten SARS‐CoV‐2 variants show significant variation in immunity profiles or endotypes. The incidence of the complete response to all variants is significantly improved after three vaccinations.
Philip H. James‐Pemberton, Shivali Kohli, Jordan Twynham, Aaron C. Westlake, Alex Antill, Rouslan V. Olkhov, Andrew M. Shaw   +6 more
wiley   +1 more source

IgG3 snitcher of RSV infections in the very young [PDF]

, 2017
Saelens, Xavier, Schepens, Bert
core   +3 more sources

Successful Treatment of Severe Purpura Fulminans With Anakinra

Pediatric Dermatology, EarlyView.
ABSTRACT Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities.
Francesco Zulian, Luca Spiezia, Antonio Amabile, Francesca Tirelli, Alessandra Meneghel   +4 more
wiley   +1 more source