Results 141 to 150 of about 265,748 (319)

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Respiratory antiviral immunity and immunobiotics: Beneficial effects on inflammation-coagulation interaction during influenza virus infection [PDF]

, 2016
Influenza virus (IFV) is a major respiratory pathogen of global importance, and the cause of a high degree of morbidity and mortality, especially in high-risk populations such as infants, elderly, and immunocompromised hosts.
Alvarez, Gladis Susana, Kitazawa, Haruki, Villena, Julio Cesar, Zelaya, María Hortensia del Rosario   +3 more
core   +1 more source

G Protein–Coupled Receptors in Olfactory Signaling and Related Disorders: Mechanisms and Therapeutic Implications

Sensory Neuroscience, EarlyView.
This schematic highlights GPCRs as the central hub of olfactory signaling in health and disease. The central GPCR shows odorant activation and downstream pathways. Surrounding quadrants illustrate four GPCR‐mediated themes: odor perception and adaptation, mucosal immunity and regeneration, memory consolidation via neural circuits, and GPCR‐related ...
Zishuo Guo, Hongjie Du, Fanyu Yuan, Yuhan Dong, Fangyuan Zhu, Jian Liu, Chengzhilin Li, Xu Guo, Zhaoze Yang, Wenwen Qi, Ming Xia, Chengcheng Liu   +11 more
wiley   +1 more source

Progression of Disease and Viral Agents in Infants Hospitalized for Lower Respiratory Tract Infections

Journal of Pediatric Research, 2019
Aim:Acute viral respiratory tract infection is the leading cause of hospitalization for infants and young children in developed countries and is a major cause of death in developing countries. The aim of this study was to identify the viruses in children
Ayşe Banu Esen, Meltem Erol, Didem Kafadar, Özlem Bostan Gayret, Özgül Yiğit, Tuğçe Damla Dilek, Kübra Yılmaz   +6 more
doaj   +1 more source

Risk factors for bronchiolitis hospitalization during the first year of life in a multicenter Italian birth cohort [PDF]

, 2015
BACKGROUND: Respiratory Syncytial Virus (RSV) is one of the main causes of respiratory infections during the first year of life. Very premature infants may contract more severe diseases and 'late preterm infants' may also be more susceptible to the ...
Adorni F, Agosti M, Arco A, Aurilia C, Barberi I, Barboni G, Bertino E, Boldrini A, Bonomi A, Bottau P, Braibanti S, Carlucci A, Corona MF, Corsello G, Corso G, Coscia A, Dall’Agnola A, De Curtis M, De Luca MG, Del Vecchio A, Di Fabio S, Di Santo S, Ellero S, Fabiano A, Fabris C, Faccia P, Faldella G, Fanos V, Gabriele B, Gargano G, Girardi E, La Forgia N, Ladetto L, Lanari M, Loprieno S, Macagno F, Magaldi R, Memo L, Molinari L, Musicco M, Natale F, Negri C, Ngalikpima CJ, Nicolini G, Nosari N, Orfeo L, Paolillo P, Parmigiani S, Piano F, Prinelli F, Puddu M, Rinaldi M, Romagnoli C, Sarnelli P, Scarcella A, Silvestri M, Spinelli M, Umbaldo A, Vandini S, Vuerich M, Zorzi G   +60 more
core   +1 more source

Nasal Delivery of mRNA Using Thermoresponsive Gellable Aqueous Biphasic Systems

Small, EarlyView.
Nasal delivery of mRNA using gellable aqueous biphasic systems (ABS) represents a noninvasive alternative while reducing the need for trained professionals and cold chain storage. Composed of gelatin, PEG, and water, these thermoresponsive hydrogels ensure controlled mRNA delivery and prolonged retention at the nasal mucosa, improving transfection ...
Bojan Kopilovic, Nabila Laroui, João A.P. Coutinho, Chantal Pichon, Mara G. Freire   +4 more
wiley   +1 more source

Immunological Lessons from Respiratory Syncytial Virus Vaccine Development.

Immunity, 2019
Respiratory syncytial virus (RSV) has eluded active vaccination efforts for more than five decades and continues to cause substantial morbidity and mortality in infants, the immunocompromised, and older adults.
T. Ruckwardt, Kaitlyn M. Morabito, B. Graham   +2 more
semanticscholar   +1 more source

Protective Role for Itaconate During Inhaled Allergen Challenge

Allergy, EarlyView.
Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers, Patricia P. Ogger, Christina Michalaki, Helen Stölting, Simone A. Walker, Anna Caldwell, John M. Halket, Kathryn Duvall, Atia Batool, Lisha Joshi, Helen O'Brien, Cormac McCarthy, Timothy Hinks, Gail M. Gauvreau, Paul M. O'Byrne, Clare M. Lloyd, Adam J. Byrne   +16 more
wiley   +1 more source

Immunization during pregnancy

Expert Review of Vaccines, 2018
Introduction: Vaccination in pregnancy has been shown to be effective for the prevention of influenza and pertussis in infants, providing support for similar strategies to prevent group B streptococcus and respiratory syncytial virus infections that ...
Paul Loubet, Olivia Anselem, Odile Launay   +2 more
doaj   +1 more source

CLINICAL AND PATHOMORPHOLOGICAL MANIFESTATIONS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION. CASE REPORT

Журнал инфектологии, 2018
On the example of clinical observation of severe respiratory syncytial virus (RSV) infection, which occurred with the development of a specific pneumonia complicated by acute respiratory distress-syndrome and disseminated intravascular coagulation ...
I. V. Babachenko, V. E. Karev, K. V. Evdokimov   +2 more
doaj   +1 more source