Results 161 to 170 of about 265,748 (319)

Trends in Hospitalisations Due to Respiratory Syncytial Virus in Swedish Children: A Nationwide Study 2010–2022

Acta Paediatrica, EarlyView.
ABSTRACT Aim Respiratory syncytial virus (RSV) infection is a leading cause of paediatric hospitalisations. This study describes annual RSV‐hospitalisation burden of disease, by gestational week of delivery, age and sex among children aged 0–17 years of age in Sweden, for the period 2010/11–2021/22.
Kristian Bolin, Karin Strandell, Andreas Palmborg, Sofie Gustafsson, Sven‐Arne Silfverdal   +4 more
wiley   +1 more source

Protectin D1 and maresin 1 attenuate airway hyperreactivity induced by IL‐13 in human isolated small bronchi

British Journal of Pharmacology, EarlyView.
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma, Sven‐Erik Dahlén, Craig E. Wheelock, Mikael Adner, Mamdoh Al‐Amerie, Erik Sachs, Kasra Vali Jalali, Leonardo De Maria, Henric Olsson, Jesper Säfholm   +9 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

The role of viral interaction in household transmission of symptomatic influenza and respiratory syncytial virus

Nature Communications
The role of viral interaction—where one virus enhances or inhibits infection with another virus—in respiratory virus transmission is not well characterized.
Jessica C. Ibiebele, Elie-Tino Godonou, Amy P. Callear, Matthew R. Smith, Rachel Truscon, Emileigh Johnson, Marisa C. Eisenberg, Adam S. Lauring, Arnold S. Monto, Sarah Cobey, Emily T. Martin   +10 more
doaj   +1 more source

Validation of the Scale for the Assessment of Illness Behavior (SAIB) in a community sample of elderly people.

, 2012
The aim of this study was to evaluate the construct validity of the SAIB in a community sample of elderly people. The SAIB was administered to a large community sample representative of the German population aged 60-85 years (n=1593).
Bhaskaran, K, Brähler, E, Engelberg, PM, Glaesmer, H, Singer, S   +4 more
core   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Risk and protective factors for meningococcal disease in adolescents: matched cohort study [PDF]

, 2006
Objective: To examine biological and social risk factors for meningococcal disease in adolescents. Design: Prospective, population based, matched cohort study with controls matched for age and sex in 1:1 matching.
Booth, C., Booy, R., Coen, P.G., Kaczmarski, E., Klein, N., Peckham, C., Stuart, J.M., Tully, J., Viner, R.M., Zambon, M.   +9 more
core  

Coinfection by influenza A virus and respiratory syncytial virus produces hybrid virus particles

Nature Microbiology, 2022
Joanne Haney, Swetha Vijayakrishnan, J. Streetley, K. Dee, D. Goldfarb, Mairi Clarke, M. Mullin, S. Carter, D. Bhella, P. Murcia   +9 more
semanticscholar   +1 more source

Characteristics of the Long‐Term Care Data Cooperative: A New Resource for Research on Outcomes in Long‐Term Care

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background The long‐term care (LTC) Data Cooperative is a National Institute on Aging‐funded data resource that links skilled nursing facility (SNF) electronic health record (EHR) data with Medicare and Medicaid claims for use in comparative effectiveness and interventional research.
Stephanie M. Kissam, Terry Hawk, Amy Recker, Catherine Rogers Murray, Dustin Burns, David D. Dore, David R. Gifford, Vincent Mor, Elizabeth M. White   +8 more
wiley   +1 more source

Impact of Nirsevimab on Respiratory Syncytial Virus PCR Test Positivity in Young Infants: A Community‐Level Observational Study in Queensland, Australia

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim In April 2024 nirsevimab, a long‐acting respiratory syncytial virus (RSV)‐specific monoclonal antibody, was made available free of charge to all newborn infants in Queensland. We aimed to explore the community‐level impact of a nirsevimab‐based prevention program on RSV detection percentages among infants aged ≤ 3 months in Queensland ...
Asmaa El‐Heneidy, Keith Grimwood, Jennifer M. Robson, Chanpaseuth Vicki Vilaylath, Sarah G. Cherian, Stephen B. Lambert, Robert S. Ware   +6 more
wiley   +1 more source