Results 171 to 180 of about 126,896 (285)

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Assessing Clinical Improvement of Infants Hospitalized for Respiratory Syncytial Virus-Related Critical Illness. [PDF]

J Infect Dis
Leland SB, Zambrano LD, Staffa SJ, McNamara ER, Newhams MM, Halasa N, Amarin JZ, Stewart LS, Shein SL, Carroll CL, Fitzgerald JC, Michaels MG, Bline K, Cullimore ML, Loftis L, Montgomery VL, Jeyapalan AS, Pannaraj PS, Schwarz AJ, Cvijanovich NZ, Zinter MS, Maddux AB, Bembea MM, Irby K, Zerr DM, Kuebler JD, Babbitt CJ, Gaspers MG, Nofziger R, Kong M, Coates BM, Schuster JE, Gertz SJ, Mack EH, White BR, Harvey H, Hobbs CV, Dapul H, Butler AD, Bradford TT, Rowan CM, Wellnitz K, Staat MA, Aguiar CL, Hymes SR, Campbell AP, Randolph AG, Respiratory Syncytial Virus - Pediatric Intensive Care (RSV-PIC) Investigators .   +47 more
europepmc   +1 more source

Novel Respiratory Disease Diagnosis Tool: Development of an Au‐ReS2‐Functionalized Extended‐gate Field‐Effect Transistor‐Type Aptasensor for Simultaneous Detection of Granzyme B and Perforin

Small Science, Volume 6, Issue 1, January 2026.
The simultaneous GzmB and PRF‐targeting EG‐FET‐type biosensor is developed for the diagnosis of respiratory diseases. The biosensor achieves femtomolar‐level detection of targets in human serum and reflects bronchial function according to cytotoxic immune activity in COPD patients. Therefore, the introduced system is proposed as an accurate, rapid, and
Seokho Jung, Minyoung Ju, Hyunjun Park, Sunggu Kang, Jungbum Kim, Yoseph Seo, Jengmin Kang, Jong Geol Jang, Jung Hyun Choi, Dong Hyung Kim, Chulhwan Park, Min‐Ho Lee, Wonhwa Lee, Taek Lee   +13 more
wiley   +1 more source

Rare case of respiratory syncytial virus induced myocarditis in a neonate: A case report. [PDF]

World J Clin Pediatr
Jaber LSK, Abu-Hamdeh M, Qouqas M, Abdullah J, Asad RM, Manhal A, Yadak DGM.   +6 more
europepmc   +1 more source

Antenatal Corticosteroid Administration and Childhood Respiratory Morbidity: A Regression Discontinuity Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 2, Page 263-271, January 2026.
ABSTRACT Objective To determine if routine administration of antenatal corticosteroids affects the risk of infant lower respiratory tract infection and/or childhood asthma. Design Linked population‐based cohort analysed using a regression discontinuity design, which better controls for confounding than standard observational studies.
Jennifer A. Hutcheon, Sam Harper, M. Claire Cordingley, Jessica Liauw, M. Amanda Skoll, Peter M. Socha, Myriam Srour, Joseph Y. Ting, Erin C. Strumpf   +8 more
wiley   +1 more source

Respiratory Syncytial Virus

Pediatric Infectious Disease, 2020
openaire   +2 more sources

Procalcitonin-guided antibiotic prescription in patients with respiratory syncytial virus and influenza virus. [PDF]

BMJ Open Respir Res
Hessels L, Vossen D, Leeuw M, Paternotte N, Karssen D, Chiang T, Terpstra L, Boersma W.   +7 more
europepmc   +1 more source

Reduced Type‐I Interferon by Plasmacytoid Dendritic Cells and Asthma in School‐Aged Children

Allergy, Volume 81, Issue 1, Page 109-120, January 2026.
Low type‐I interferon response to in vitro stimulation of plasmacytoid dendritic cells (pDC) with a TLR7/8 agonist (R848) is associated with current asthma in school‐aged children. Low type‐I interferon response is associated with increased level of atopy but appears to have limited impact on early life viral infection susceptibility.
Isabelle Coenen, Anya C. Jones, Alice A. White, Mari Takashima, Wen Ray Lee, Matthew D. Wong, Dwan Vilcins, Ulrich Kadolsky, Ali Sadiq Cheema, Alka Saxena, Anthony Bosco, Keith Grimwood, Peter D. Sly, Deborah H. Strickland, Jonatan Leffler   +14 more
wiley   +1 more source

Markers in Infants of Mothers With Asthma and Associations With Respiratory Outcomes

Allergy, Volume 81, Issue 1, Page 145-156, January 2026.
In the BILD and BLT cohorts, we compared cord blood proteins in infants of mothers with and without asthma during pregnancy. Groups showed different protein levels. These markers were associated with postnatal lung function, bronchiolitis hospitalization, and asthma.
Carla Rebeca Da Silva Sena, Gabriela Martins Costa Gomes, Noëmi Künstle, Olga Gorlanova, Andrea Marten, Sven Schulzke, Florian Wyler, Vanessa E. Murphy, Paul D. Robinson, Peter D. Sly, Jakob Usemann, Benjamin Stoecklin, Ruth Steinberg, Sophie Yammine, Loretta Müller, Philipp Latzin, Pablo Sinues, Peter G. Gibson, Joerg Mattes, Adam Collison, Urs Frey, on behalf of the BILD and BLT Study Groups   +21 more
wiley   +1 more source

Immune Training of the Interleukin 6 Gene in Airway Epithelial Cells is Central to Asthma Exacerbations

Allergy, Volume 81, Issue 1, Page 157-169, January 2026.
This study aims to investigate how immune activation influences the epigenetic regulation and expression of the Interleukin‐6 (IL‐6) gene during asthma exacerbations. By examining molecular mechanisms of immune training, we seek to elucidate how IL‐6‐driven inflammatory pathways contribute to airway dysfunction and worsening asthma symptoms.
Lars P. Lunding, Markus Weckmann, Ulrich M. Zissler, Constanze Jakwerth, Rebecca Bodenstein‐Sgró, Sina Webering, Christina Vock, Johanna C. Ehlers, Romina A. M. Fernandez Ceballos, Sai Sneha Priya Nemani, Karosham Diren Reddy, Brian George G. Oliver, Cornelis J. Vermeulen, Maarten van de Berge, Carole Ober, Axel Künstner, Hauke Busch, Inke König, Christoph Garbers, Carsten B. Schmidt‐Weber, Marcel F. Nold, Ali Önder Yildirim, Claudia A. Nold‐Petry, Zane Orinska, Thomas Bahmer, Jan Heyckendorf, Gesine Hansen, Erika von Mutius, Klaus F. Rabe, Anna‐Maria Dittrich, Bianca Schaub, Folke Brinkmann, Matthias V. Kopp, Michael Wegmann, The ALLIANCE Study Group as part of the German Centre for Lung Research (DZL)   +34 more
wiley   +1 more source